• 沒有找到結果。

第五章 結論與建議

第二節 建議

本研究因AMD 患者的數目並不足以將 AMD 族群進一步的區分為 dry AMD 和 wet AMD 兩種表現型,所以將所有的 AMD 患者的報告結果一起分析,此外,有些 SNP 基因型分佈機率相當的罕見,所以需要更大的樣本數來加以確認實驗的結果,

並且也可以將AMD 患者區分為 dry AMD 和 wet AMD 兩種表現型來觀察這些基因之 多型性在兩族群之間的分佈是否有所差異存在。進一步的研究,可測定這些實驗對

象,其血清中 VEGF,TNF-α 及其他細胞激素的濃度來證明我們的推測是否正確,

未來,可進一步地研究這些基因在眼球組織的表現,如轉錄的速率,mRNA 的穩定

性及蛋白質的表現等等,以更了解AMD 致病機轉,尋求更有效的預防及治療方式。

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