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課程綱要一、開課名稱(中英文並列)腫瘤生物學導論Introduction of Tumor Biology

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課程綱要

一、開課名稱

(中英文並列)

腫瘤生物學導論

Introduction of Tumor Biology 學分數

2

二、開課教授 賴金美 開課年級:生命科學系 四 年級

三、課程目標

(中英文並列)

本門課程將對基礎的分子生物學、細胞學及生物化學做概括性的復 習與整理,以期引領大學學生做為準備研究所考試或為日後在研究 所的課程與研究做準備。從涵蓋腫瘤生物學的角度做出發,盼給予 同學在現今分子醫學領域有一宏觀的知識與概念。

The fundamental molecular biology, cell biology, and biochemistry

themes will be reviewed and integrated in this course. We aim to guide the undergraduate students to prepare and to the acquisition graduate studies in biomedical research. From the theme covered in tumor biology, the students will have a broad spectrum of knowledge in current molecular and medical research.

四、課程綱要

1. 腫瘤生物學概述。

2. Phenotypic characteristics of cancer cell.

3. chemicals, radiation, and infectious agents in carcinogenesis.

4. 致癌基因與抑癌基因(Oncogene/ Tumor suppressor)介紹。

5. Cell cycle regulation and cancer.

6. Apoptosis in cancer.

7. 癌症轉移(metastasis)與血管新生(angiogenesis)。

8. Signal transduction in tumorgenesis.

9. Clinical lecture: 常見癌症的診斷與治療。

10. Cancer stem cells.

11. 癌症之預防與治療 12.腫瘤醫學之研究方法。

五、Reference 1. Principles of Cancer Biology

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(ISBN-10: 0805340033 | ISBN-13: 978-0805340037).

2. The Biology of Cancer

(ISBN-10: 0815340788 | ISBN-13: 978-0815340782)

 授課方式:(課堂講解)

以「Principles of Cancer Biology」為課本,逐章講解,並連貫已修 習之細胞學、生化及分子生物學等知識,以期導入腫瘤、癌症醫學 概念之際,亦復習並貫通基礎學科於癌症醫學之應用。為使同學對 臨床的診斷及治療亦有所概念,學期中亦增加 Clinical lectures,延 請數位常見癌症的臨床醫師蒞臨指導,讓同學擁有理論與實際並行 的課程規劃。

 評分標準:期中考(40%);期末報告(40%);出席率(20%)

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