Effects of complete nutritional supplement on nutrit ional and physiological status in hemodialysis patie nts

完整營養補充劑對於血液透析患者營養及生理狀況 之影響

Effects of complete nutritional supplement on nutrit ional and physiological status in hemodialysis patie

nts



The present study was designed to evaluate the effect of complete nutritional supplement on selected nutritional and physiolog ical variables in hemodialysis (HD) patients. Nineteen adult HD patients were on regular three times weekly HD for at least 3 months. Patients were followed for a 1-month baseline period, this was before an intervention period, during which, patients were asked to incorporate 100 g of complete nutritional supplement (providing 460 kcal and 18 g protein) daily for 1 month. P atients were reevaluated at third months. A 4 days dietary record was performed over baseline and intervention period. The m ain outcome measures including anthropometry, blood data, dietary intake, Kt/V, subjective scoring for appetite, and toleranc e to supplement were obtained during the 3-month period. Patients incorporated mean 67g complete nutritional supplement ov er intervention period. This resulted in the energy intake rose to 30 kcal/kg body weight/day (P < 0.05). Following administrat ion of complete nutritional supplement, there were significant increases in concentrations of serum total protein, transferrin, bl ood urea nitrogen and body fat (P < 0.05). Kt/V, subjective scoring for appetite, the concentrations of blood bicarbonate, and neutrophile count did not change during the study period. Complete nutritional supplement was shown to bring about a signifi cant improvement in some selected nutritional markers such as serum total protein, transferrin, blood urea nitrogen and body f at in chronic HD patients, and does not effect the physiological variables of patients.

The present study was designed to evaluate the effect of complete nutritional supplement on selected nutritional and physiolog

ical variables in hemodialysis (HD) patients. Nineteen adult HD patients were on regular three times weekly HD for at least 3

months. Patients were followed for a 1-month baseline period, this was before an intervention period, during which, patients

were asked to incorporate 100 g of complete nutritional supplement (providing 460 kcal and 18 g protein) daily for 1 month. P

atients were reevaluated at third months. A 4 days dietary record was performed over baseline and intervention period. The m

ain outcome measures including anthropometry, blood data, dietary intake, Kt/V, subjective scoring for appetite, and toleranc

e to supplement were obtained during the 3-month period. Patients incorporated mean 67g complete nutritional supplement ov

er intervention period. This resulted in the energy intake rose to 30 kcal/kg body weight/day (P < 0.05). Following administrat

ion of complete nutritional supplement, there were significant increases in concentrations of serum total protein, transferrin, bl

ood urea nitrogen and body fat (P < 0.05). Kt/V, subjective scoring for appetite, the concentrations of blood bicarbonate, and

neutrophile count did not change during the study period. Complete nutritional supplement was shown to bring about a signifi

cant improvement in some selected nutritional markers such as serum total protein, transferrin, blood urea nitrogen and body f

at in chronic HD patients, and does not effect the physiological variables of patients.