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[PDF] Top 20 Chloroacetic acid induced cell apoptosis through ROS/endoplasmic reticulum stress pathway in neuronal cell

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Chloroacetic acid induced cell apoptosis through ROS/endoplasmic reticulum stress pathway in neuronal cell

Chloroacetic acid induced cell apoptosis through ROS/endoplasmic reticulum stress pathway in neuronal cell

... Treatment of Neuro-2a cells with CA for 24h significantly induced cytotoxicity, reduced cell viability, and oxidative stress damage (membrane LPO production) which accompanied by sever[r] ... See full document

2

Chloroacetic acid triggers apoptosis in neuronal cells via a reactive oxygen species-induced endoplasmic reticulum stress signaling pathway

Chloroacetic acid triggers apoptosis in neuronal cells via a reactive oxygen species-induced endoplasmic reticulum stress signaling pathway

... cause neuronal cell death via the activation of ER stress pathways, which may contribute to neurodegeneration ...ER stress-mediated apoptotic signals in CA-induced ... See full document

39

Arsenic induces apoptosis in myoblasts through a reactive oxygen species-induced endoplasmic reticulum stress and mitochondrial dysfunction pathway

Arsenic induces apoptosis in myoblasts through a reactive oxygen species-induced endoplasmic reticulum stress and mitochondrial dysfunction pathway

... oxidative stress can effectively induce cell apoptosis through activation of the endoplasmic reticulum (ER) stress pathway (Lu et ...leads cell ... See full document

11

Cantharidin induces apoptosis through the calcium/PKC-regulated endoplasmic reticulum stress pathway in human bladder cancer cells

Cantharidin induces apoptosis through the calcium/PKC-regulated endoplasmic reticulum stress pathway in human bladder cancer cells

... decreased cell viability. The expressions of increase in caspase-3 activity and cleaved form of caspase-9/-7/-3 were also increased in cantharidin-treated T24 ...increase in calpain activity ... See full document

29

Chloroacetic acid induced neuronal cells death through oxidative stress-mediated p38-MAPK activation pathway regulated mitochondria-dependent apoptotic signals

Chloroacetic acid induced neuronal cells death through oxidative stress-mediated p38-MAPK activation pathway regulated mitochondria-dependent apoptotic signals

... inducing neuronal cell death, and more importantly reveal the underlying molecular basis of its ...triggers cell death through mitochondria dysfunction, which leads to activations of PARP and ... See full document

52

Kaempferol induced apoptosis via endoplasmic reticulum stress and mitochondria-dependent pathway in human osteosarcoma U-2 OS cells.

Kaempferol induced apoptosis via endoplasmic reticulum stress and mitochondria-dependent pathway in human osteosarcoma U-2 OS cells.

... on cell morphological changes, DNA damage and apoptosis in human osteosarcoma U-2 OS cells To investigate the occurrence of morphological changes and DNA damage in human osteosarcoma cells, we ... See full document

11

FPTB, a Novel CA-4 Derivative, Induces Cell Apoptosis of Human Chondrosarcoma Cells Through Mitochondrial Dysfunction and Endoplasmic Reticulum Stress Pathways

FPTB, a Novel CA-4 Derivative, Induces Cell Apoptosis of Human Chondrosarcoma Cells Through Mitochondrial Dysfunction and Endoplasmic Reticulum Stress Pathways

... FPTB-induced cell apoptosis is mediated through mitochondrial dysfunction, we determined the mitochondrial membrane potential with the mitochondria-sensitive dye, JC-1, using fluorescence ... See full document

24

Ellagic acid induces apoptosis in tsgh8301 human bladder cancer cells through the endoplasmic reticulum stress- and mitochondria-dependent signaling pathways

Ellagic acid induces apoptosis in tsgh8301 human bladder cancer cells through the endoplasmic reticulum stress- and mitochondria-dependent signaling pathways

... that apoptosis is a programmed cell death which involves multiple steps and complex interactions of molecular events and then finally leads to the activation of cell-intrinsic suicide machinery ... See full document

13

Baicalein-Induced Apoptosis via Endoplasmic Reticulum Stress Through Elevations of Reactive Oxygen Species and Mitochondria Dependent Pathway in Mouse-Rat Hybrid Retina Ganglion Cells (N18)

Baicalein-Induced Apoptosis via Endoplasmic Reticulum Stress Through Elevations of Reactive Oxygen Species and Mitochondria Dependent Pathway in Mouse-Rat Hybrid Retina Ganglion Cells (N18)

... OXIDATIVE STRESS; LEUKEMIA-CELLS; ANNEXIN-V; DYSFUNCTION; MECHANISMS; FLAVONOIDS Abstract: Studies were designed to investigate the effects of baicalein on mouse-rat hybrid retina ganglion cells (N18) to better ... See full document

3

DNA damage and endoplasmic reticulum stress mediated curcumin-induced cell cycle arrest and apoptosis in human lung carcinoma A-549 cells through the activation caspases cascade- and mitochondrial-dependent pathway (vol 272, pg 77, 2008)

DNA damage and endoplasmic reticulum stress mediated curcumin-induced cell cycle arrest and apoptosis in human lung carcinoma A-549 cells through the activation caspases cascade- and mitochondrial-dependent pathway (vol 272, pg 77, 2008)

... Technol, Taichung 404, Taiwan; [Lin, Song-Shei] Cent Taiwan Univ Sci & Technol, Dept Radiol Technol, Taichung 40605, Taiwan; [Yang, Jai-Sing] China Med Univ, Dept Pharmacol, Taichu[r] ... See full document

2

Capsaicin mediates apoptosis in human naspharyngeal carcinoma NPC-TW 039 cells through mitochondrial depolarization and endoplasmic reticulum stress

Capsaicin mediates apoptosis in human naspharyngeal carcinoma NPC-TW 039 cells through mitochondrial depolarization and endoplasmic reticulum stress

... found in hot chili peppers, has been reported to have antitumor activities in many human cancer cell lines, but the induction of precise apoptosis signaling pathway in human ... See full document

11

The roles of endoplasmic reticulum stress and mitochondrial apoptotic signaling pathway in quercetin-mediated cell death of human prostate cancer PC-3 cells

The roles of endoplasmic reticulum stress and mitochondrial apoptotic signaling pathway in quercetin-mediated cell death of human prostate cancer PC-3 cells

... μM), cell morphology and viability decreased significantly in dose-dependent ...quercetin induced G0/G1 phase arrest via decreased the protein expression of CDK2, CDK4, cyclins E and B ...apoptotic ... See full document

1

Rhein Induced Apoptosis through the Endoplasmic Reticulum Stress, Caspase- and Mitochondria-dependent Pathways in SCC-4 Human Tongue Squamous Cancer Cells

Rhein Induced Apoptosis through the Endoplasmic Reticulum Stress, Caspase- and Mitochondria-dependent Pathways in SCC-4 Human Tongue Squamous Cancer Cells

... Rhein; apoptosis; caspase; mitochondria; DNA damage; SCC-4 human tongue cancer cells KeyWords Plus: ACTIVATION; PROTEOLYSIS; PROTEASES Abstract: Rhein, an anthraquinone compound, can be found in the rhizome ... See full document

3

Diallyl disulfide induces apoptosis in human colon cancer cell line (COLO 205) through the induction of reactive oxygen species, endoplasmic reticulum stress, caspases casade and mitochondrial-dependent pathways

Diallyl disulfide induces apoptosis in human colon cancer cell line (COLO 205) through the induction of reactive oxygen species, endoplasmic reticulum stress, caspases casade and mitochondrial-dependent pathways

... Abstract: In this study, we investigated the effects of DADS on human colon cancer cell line COLO 205 on cell cycle arrest and apoptosis in ...of ROS. Treatment of COLO 205 cells ... See full document

3

The novel phloroglucinol derivative BFP induces apoptosis of glioma cancer through reactive oxygen species and endoplasmic reticulum stress pathways

The novel phloroglucinol derivative BFP induces apoptosis of glioma cancer through reactive oxygen species and endoplasmic reticulum stress pathways

... BFP induced cell death and anti-proliferation in three glioma, U251, U87 and C6 cells, but not in primary human ...concentration-dependently cell death in glioma cells was ... See full document

8

The Roles of Endoplasmic Reticulum Stress and Ca2+ on Rhein-induced apoptosis in A-549 Human Lung Cancer cells

The Roles of Endoplasmic Reticulum Stress and Ca2+ on Rhein-induced apoptosis in A-549 Human Lung Cancer cells

... induce apoptosis in several cancer cell lines, the mechanism of action of rhein-induced cell cycle arrest and apoptosis at the molecular level is not well ...known. In ... See full document

3

Genistein induces apoptosis in human hepatocellular carcinomas via interaction of endoplasmic reticulum stress and mitochondrial insult.

Genistein induces apoptosis in human hepatocellular carcinomas via interaction of endoplasmic reticulum stress and mitochondrial insult.

... inhibited in cells transfected with antisense GADD153 cDNA, indicating a functional role of ...genistein induced the activation of caspase-2, whereas did not cause the DNA ...of ROS. The antioxidant ... See full document

11

Wogonin triggers apoptosis in human osteosarcoma U-2 OS cells through the endoplasmic reticulum stress, mitochondrial dysfunction and caspase-3-dependent signaling pathways.

Wogonin triggers apoptosis in human osteosarcoma U-2 OS cells through the endoplasmic reticulum stress, mitochondrial dysfunction and caspase-3-dependent signaling pathways.

... mechanisms in wogonin-induced apoptosis of U-2 OS human osteosarcoma cells is unclear and it remains to be ...of apoptosis and protein levels which are involved in apoptotic cell ... See full document

8

Bisdemethoxycurcumin-induced S phase arrest through the inhibition of cyclin A and E and induction of apoptosis via endoplasmic reticulum stress and mitochondria-dependent pathways in human lung cancer NCI H460 cells.

Bisdemethoxycurcumin-induced S phase arrest through the inhibition of cyclin A and E and induction of apoptosis via endoplasmic reticulum stress and mitochondria-dependent pathways in human lung cancer NCI H460 cells.

... decreased cell number (cytotoxic effect) on human lung cancer NCI H460 cells, mediated through S phase arrest via inhibited CDC25A, cyclin A and E and CDK2 and induction of apoptosis through ... See full document

25

The role of endoplasmic reticulum in cadmium-induced mesangial cell apoptosis

The role of endoplasmic reticulum in cadmium-induced mesangial cell apoptosis

... ER stress would be expected to lead to cell death. In the present study, the chelating of cytosolic calcium by BAPTA-AM decreased not only the percentage of cells undergoing apopto- sis, but also the ... See full document

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