[PDF] Top 20 Physiological regulation of Akt activity and stability
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Physiological regulation of Akt activity and stability
... as Akt) constitutes an important node in diverse signaling cascades downstream of growth factor receptor tyrosine ...kinases. Akt plays an essential role in cell survival, growth, migration, ... See full document
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Peptidyl-prolyl cis/trans isomerase Pin1 is critical for the regulation of PKB/Akt stability and activation phosphorylation
... In this study, we showed a strong correlation between the expression levels of an oncogenic peptidyl-prolyl cis/trans isomerase Pin1 and levels of Akt phosphorylation at S473 in multip[r] ... See full document
3
Regulation of the activity of p38 mitogen-activated protein kinase by Akt in cancer and adenoviral protein E1A-mediated sensitization to apoptosis
... UV and gamma irradiation, and different categories of anticancer ...inactivation of a key survival factor Akt and the activation of a pro-apoptotic factor ...inactivation ... See full document
1
AKT3 promotes prostate cancer proliferation cells through regulation of Akt, B-Raf, and TSC1/TSC2
... target of rapamycin (mTOR) activity and increase translation under hypoxic conditions ...mTOR activity and protein synthesis does not translate into enhanced cell proliferation rates, ... See full document
1
Induction of Akt Activity by Chemotherapy Confers Acquired Resistance
... minutes and, reached a plateau at 3 hours, and declined ...activation of Akt by paclitaxel mediates the following inhibitory regulation and phosphorylation of Raf-1, ... See full document
1
Induction of Akt activity by chemotherapy confers acquired resistance
... cause of treatment failure in human ...acquisition of resistance to chemotherapeutic drugs involves the activation of the PI3K/Akt ...Modulating Akt activity in response to ... See full document
1
Induction of Akt Activity by Chemotherapy Confers Acquired Resistance
... Activation of this pathway evades the cytotoxic effects of chemotherpeutic agents via regulation of essential cellular functions such as protien synthesis, antiapoptosis, survival and ... See full document
6
Differential regulation of ARE-mediated TNFα and IL-1β mRNA stability by lipopolysaccharide in RAW264.7 cells
... expression and influence cell growth and dif- ...cytokine, and growth factor RNAs contain AU-rich element (AREs) in the 3 0 untranslated regions which enable them to be targeted for rapid ...mechanism ... See full document
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Induction of Akt Activity by Chemotherapy Confers Acquired Resistance Wei-Chien Huang
... cause of treatment failure in human ...acquisition of resistance to chemotherapeutic drugs involves the activation of the PI3K/Akt ...Modulating Akt activity in response to ... See full document
23
Down-regulation of Fatty Acid Synthase Is Associated with Decreased Akt Activation in Lovastatin Induced Apoptosis Cells
... apoptosis-inducing activity in HL-60 cells, as observed by flow cytometry (with ...morphology, and nuclear condensation. Cellular triglyceride, cholesterol, and free fatty acid in HepG2 cells were ... See full document
1
Shikonin inhibits oxidized LDL-induced monocyte adhesion by suppressing NFkB activation via up-regulation of PI3K/Akt/Nrf2-dependent antioxidation in EA.hy926 endothelial cells
... isolated from the Chinese herb Lithospermum erythrorhizon, has been shown to possess cardioprotective, antioxidative, and anti-inflammatory effects, the mechanisms underlying these actions are not well understood. ... See full document
3
Physiological and pathophysiological regulation of cytochrome P450.
... Approaches and systems used to address these questions included conditional gene knockouts in mice, primary hepatocyte cultures, immunofluorescence imaging of cells, and cell lines sta[r] ... See full document
1
Structure, regulation and physiological roles of urea transporters.
... constituent of the urine and the principal means for disposal of nitrogen derived from amino acid ...medulla and play a central role in urea excretion and water ...accumulation ... See full document
1
Vegetation water-soluble polysaccharide from Cordyceps composition and physiological activity of eng
... Chinese caterpillar fungus spores nunchakus vegetation (Phytocordyceps ninchukispora Suet Wang) is Clavicipitaceae ball.. Globosum projects, nuclear Basidiomycetes, system is the recent[r] ... See full document
1
Physiological Role of the Association Complexes of α-Crystallin and Its Substrates on the Chaperone Activity
... presence of a -crystallin preincubated at 60 7C for 20 min; and (D) tion, however the reaction intermediates are different in both g -crystallin and a -crystallin preincubated at 60 7C for 20 min ... See full document
5
Oxygen- and growth rate-dependent regulation of Escherichia coli fumarase (FumA, FumB, and FumC) activity
... interconversion of fumarate to L -malate in the tricarboxylic acid ...substrate and cell doubling time. Growth rate control of fumarase activities in the wild type and mutants was demonstrated ... See full document
7
Abeta(25-35) alters Akt activity, resulting in Bad translocation and
... We applied three strategies to show that Abeta25-35 inactivation of Akt is causally related to Abeta25-35-induced CEC death by preventing Bad activation and subsequent mitochondrial dy[r] ... See full document
1
Abeta(25-35) alters Akt activity, resulting in Bad translocation and
... We applied three strategies to show that Abeta25-35 inactivation of Akt is causally related to Abeta25-35-induced CEC death by preventing Bad activation and subsequent mitochondrial dy[r] ... See full document
1
Enhancing Stability and Oxidation Activity of Cytochrome C By Immobilization in the Nanochannels of Mesoporous Aluminosilicates
... application of MPS materials to encapsulate a hydroxo-bridged di-nuclear phenanthroline cupric complex to mimic catechol ...diameters and accessible surface modification with functional groups and ... See full document
10
Keywords: edible and medicinal mushroom, solid fermentation technique, soybean, soybean meal, health food, physiological (2)activity
... the physiological activities of soybean using edible and medicinal mushroom Edible and medicinal mushroom that are palatable, nutritious and rich in physiologically active substances ... See full document
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