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[PDF] Top 20 suppressing the expression of matrix metalloproteinase-9Heme oxygenase-1 inhibits breast cancer invasion via

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suppressing the expression of matrix metalloproteinase-9Heme oxygenase-1 inhibits breast cancer invasion via

suppressing the expression of matrix metalloproteinase-9Heme oxygenase-1 inhibits breast cancer invasion via

... supports the cytoprotective and anti- inflammatory actions of HO-1 in vitro and in ...to the role of HO-1 in tumor progression are still ...Induction of HO-1 by ... See full document

13

Heme oxygenase-1 inhibits breast cancer invasion via suppressing the expression of matrix metalloproteinase-9

Heme oxygenase-1 inhibits breast cancer invasion via suppressing the expression of matrix metalloproteinase-9

... stimulation of reactive oxygen species production was involved in TPA-induced invasion of MCF-7 cells, which was attenuated by HO-1 protein induced by ferric protoporphyrin IX or transfection ... See full document

1

Heme oxygenase-1 inhibits breast cancer invasion via suppressing the expression of matrix metalloproteinase-9.

Heme oxygenase-1 inhibits breast cancer invasion via suppressing the expression of matrix metalloproteinase-9.

... In the present study, we investigated the antitumor effects of the invasiveness and migration of heme oxygenase 1 (HO-1) in human breast carcinoma ... See full document

1

CHM-1 inhibits hepatocyte growth factor-induced invasion of SK-Hep-1 human hepatocellular carcinoma cells by suppressing matrix metalloproteinase-9 expression.

CHM-1 inhibits hepatocyte growth factor-induced invasion of SK-Hep-1 human hepatocellular carcinoma cells by suppressing matrix metalloproteinase-9 expression.

... induce the production of MMPs. It has shown that elevated serum levels of MMP-9 in HCC patients and over- expression of MMP-9 in HCC tissues are related to hematogenous ... See full document

10

Quercetin inhibition of tumor invasion via suppressing PKCd/ERK/AP-1-dependent matrix metalloproteinase-9 activation in breast carcinoma cells

Quercetin inhibition of tumor invasion via suppressing PKCd/ERK/AP-1-dependent matrix metalloproteinase-9 activation in breast carcinoma cells

... suppression of MMP-9 expression To investigate the SARs of QUE against MMP-9 expression, the related structural analogs of QUE were employed and are depicted ... See full document

9

Inhibition of matrix metalloproteinase-9 expression by docosahexaenoic acid mediated by heme oxygenase 1 in 12-O-tetradecanoylphorbol-13-acetate-induced MCF-7 human breast cancer cells

Inhibition of matrix metalloproteinase-9 expression by docosahexaenoic acid mediated by heme oxygenase 1 in 12-O-tetradecanoylphorbol-13-acetate-induced MCF-7 human breast cancer cells

... Cordycepin inhibits TPA-induced matrix metalloproteinase-9 expression by suppressing the MAPK/AP-1 pathway in MCF-7 human breast cancer ... See full document

34

Osthole inhibits the invasive ability of human lung adenocarcinoma cells via suppression of NF-κB-mediated matrix metalloproteinase-9 expression

Osthole inhibits the invasive ability of human lung adenocarcinoma cells via suppression of NF-κB-mediated matrix metalloproteinase-9 expression

... adenocarcinoma The induction of matrix metalloproteinase (MMP)-9 is particularly important for the invasiveness of various cancer ...inhibit the ... See full document

11

Benzyl isothiocyanate (BITC) inhibits migration and invasion of human gastric cancer AGS cells via suppressing ERK signal pathways

Benzyl isothiocyanate (BITC) inhibits migration and invasion of human gastric cancer AGS cells via suppressing ERK signal pathways

... activation of different intracellular-signaling path- ways. The activation of PKC led to translocation of the protein to membranes and for the control of MMP-9 ... See full document

12

Gallic acid inhibits migration and invasion in human osteosarcoma U-2 OS cells through suppressing the matrix metalloproteinase-2/-9, protein kinase B (PKB) and PKC signaling pathways

Gallic acid inhibits migration and invasion in human osteosarcoma U-2 OS cells through suppressing the matrix metalloproteinase-2/-9, protein kinase B (PKB) and PKC signaling pathways

... explore the exact expression of GA-induced inhibi- tion of invasion and migration, we performed a gelatin zymogra- phy assay to detect the activities of MMP-2 and ... See full document

7

Crude extract of Euphorbia formosana inhibits the migration and invasion of DU145 human prostate cancer cells: The role of matrix metalloproteinase-2/9 inhibition via the MAPK signaling pathway.

Crude extract of Euphorbia formosana inhibits the migration and invasion of DU145 human prostate cancer cells: The role of matrix metalloproteinase-2/9 inhibition via the MAPK signaling pathway.

... suppressed the migration and invasion of DU145 prostate cancer cells and that these effects are exerted in a concentration- and time-dependent ...inhibited the ERK1/2, p38, JNK, ... See full document

12

Lycopene inhibits matrix metalloproteinase-9 expression and down-regulates the binding activity of nuclear factor k B and stimulatory protein 1

Lycopene inhibits matrix metalloproteinase-9 expression and down-regulates the binding activity of nuclear factor k B and stimulatory protein 1

... activity via down- regulation of the expression of matrix metalloproteinase (MMP)-9, an important enzyme in the degradation of basement membrane in ... See full document

1

Gypenosides inhibits migration and invasion of human oral cancer SAS cells through the inhibition of matrix metalloproteinase-2/ -9 and urokinase-plasminogen by ERK1/2 and NF-kappa B signaling pathways

Gypenosides inhibits migration and invasion of human oral cancer SAS cells through the inhibition of matrix metalloproteinase-2/ -9 and urokinase-plasminogen by ERK1/2 and NF-kappa B signaling pathways

... cell invasion, matrix metalloproteinase-2 -9, urokinase-plasminogen, SAS cells Introduction Over 300,000 cases of oral and oropharyngeal cancers are diagnosed annually ...worldwide. ... See full document

10

Quercetin inhibition of tumor invasion via suppressing PKC delta/ERK/AP-1-dependent matrix metalloproteinase-9 activation in breast carcinoma cells

Quercetin inhibition of tumor invasion via suppressing PKC delta/ERK/AP-1-dependent matrix metalloproteinase-9 activation in breast carcinoma cells

... activation of the PKCdelta/ERK/AP-1-signaling ...elucidate the importance of hydroxyl (OH) substitutions to QUE's inhibition of tumor migration, several structurally related ... See full document

1

Quercetin inhibition of tumor invasion via suppressing PKC/ERK/AP-1-dependent matrix metalloproteinase-9 activation in breast carcinoma cells.

Quercetin inhibition of tumor invasion via suppressing PKC/ERK/AP-1-dependent matrix metalloproteinase-9 activation in breast carcinoma cells.

... A translocation of protein kinase C (PKC)delta from the cytosol to the membrane followed by activation of extracellular signal-regulated kinase (ERK) and c-Jun/activator protein-1 (AP-[r] ... See full document

1

Quercetin inhibition of tumor invasion via suppressing PKC delta/ERK/AP-1-dependent matrix metalloproteinase-9 activation in breast carcinoma cells.

Quercetin inhibition of tumor invasion via suppressing PKC delta/ERK/AP-1-dependent matrix metalloproteinase-9 activation in breast carcinoma cells.

... activation of the PKC/ERK/AP-1 signaling cascade. To elucidate the importance of OH substitutions to QUE's inhibition of tumor migration, several structurally related flavones ... See full document

1

Deguelin Inhibits the Migration and Invasion of U-2 OS Human Osteosarcoma Cells via the Inhibition of Matrix Metalloproteinase-2/-9 in Vitro

Deguelin Inhibits the Migration and Invasion of U-2 OS Human Osteosarcoma Cells via the Inhibition of Matrix Metalloproteinase-2/-9 in Vitro

... activate the Ras-ERK signaling pathway ...through the RAS/RAF/MEK/ERK cascade are involved in the development of hepatocellular carcinoma cells and in the regulation of cell ... See full document

30

Gallic acid suppresses the migration and invasion of PC-3 human prostate cancer cells via inhibition of matrix metalloproteinase-2 and -9 signaling pathways

Gallic acid suppresses the migration and invasion of PC-3 human prostate cancer cells via inhibition of matrix metalloproteinase-2 and -9 signaling pathways

... consumption of fruits or vegetables can decrease the risk of cancer ...development. cancer cells can migrate to and invade other organs or tissues that cause more difficulty to treat ... See full document

8

Melatonin inhibits postischemic matrix metalloproteinase-9

Melatonin inhibits postischemic matrix metalloproteinase-9

... suggests the involvement of this protease in the pathogenesis of ischemic brain damage [10, ...Thus, the melatonin-induced decrease of u-PA levels and the increase ... See full document

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血紅素氧化酵素抑制乳癌侵犯之機制 Anti-Tumor Invasion of Heme Oxygenase-1 in Human Breast Cancer

血紅素氧化酵素抑制乳癌侵犯之機制 Anti-Tumor Invasion of Heme Oxygenase-1 in Human Breast Cancer

... Anti-Tumor Invasion of Heme Oxygenase-1 in Human Breast Cancer 中文摘要 血紅素氧化酵素(Heme oxygenase-1; HO-1)是體內重要的細胞保護與氧化壓力誘 ... See full document

1

血紅素氧化酵素抑制乳癌侵犯之機制 Anti-Tumor Invasion of Heme Oxygenase-1 in Human Breast Cancer

血紅素氧化酵素抑制乳癌侵犯之機制 Anti-Tumor Invasion of Heme Oxygenase-1 in Human Breast Cancer

... Anti-Tumor Invasion of Heme Oxygenase-1 in Human Breast Cancer 中文摘要 血紅素氧化酵素(Heme oxygenase-1; HO-1)是體內重要的細胞保護與氧化壓力誘 ... See full document

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