建議

由研究結果可發現，在使用金屬加工液切削機台附近的勞工，會有 高濃度的細菌暴露，雖然不一定會造成健康方面的影響，但從文獻可得 知，操作機台的勞工也有可能會因為吸入金屬加工液中之微生物而導致 過敏性肺炎⁽⁴⁶⁾，或因接觸金屬加工液而有過敏性皮膚炎之情況之發生

(23)(24)(50)。因此建議可使從業勞工佩戴密合度高之口罩及適當之防護手

套，以降低勞工可能的暴露風險，至於其防護效能則需進一步研究。未 來將對金屬加工液中細菌菌種濃度分佈情形及相關從業勞工健康效應做 進一步之評估。

參考文獻

(1) ACGIH. Guidelines for the Assessment of Bioaerosols in the Indoor Environment. American Conference of Governmental Industrial Hygienists. 1989.

(2) 張靜文。空氣中生物性危害與呼吸防護(下)。北市衛生；1999; 46:

19-22。

(3) NIOSH. Criteria for Recommended Standard Occupational Exposure to Metalworking Fluids. National Institute of Occupational Safety and Health, Cincinnati, Ohio. 1998.

(4) Wang HX, Reponen T, Li W, Martuzevicius D, Grinshpun SA, and Willeke K. Aerosolization of fine particles increases due to microbial contamination of metalworking fluids. Journal of Aerosol Science. 2005;

36: 724-734.

(5) Kriebel D, Eberiel D, Eisen EA, Eraso RM, Kumar S, Sama S, et al. Field investigations of the acute respiratory effects of machining fluids. Final report to the UAW-GM National Joint Committee on Safety and Health, June 1, 1994.

(6) Greaves IA, Eisen EA, Smith TJ, Pothier LJ, Kriebel D, Woskie SR, et al.

(1995a). Respiratory health of automobile workers and exposures to metal-working fluid aersols. III. Lung spirometry. Boston, MA: Harvard School of Public Health, Occupational Health Program. Final Draft.

1995.

(7) Greaves IA, Eisen EA, Smith TJ, Pothier LJ, Kriebel D, Woskie SR, et al.

(1995b). Respiratory health of automobile workers exposed to metal-working fluid aerosols. II. Respiratory symptoms. Boston, MA:

Harvard School of Public Health, Occupational Health Program. Final Draft. 1995.

Respiratory effects of machining fluid aerosols. Final report to the UAW-GM Occupational Health Advisory Board. 1994.

(9) ANSI. American national standard technical report: mist control considerations for the design, installation, and use of machine tools using metalworking fluids. American National Standard Institute, B11 Ventilation Subcommittee, ANSI B11 TR 2-1997 New York, NY. 1997.

(10) Stear MA. Controlling health risk from workplace exposure to metalworking fluids in the United Kingdom engineering industry.

Applied Occupational and Environmental Hygiene. 2003; 18: 877-882.

(11) 中華民國統計資訊網(URL: http://www.stat.gov.tw/ct.asp?xItem=1683&ctNode=543)

(12) Simpson AT, Groves JA, Unwin J, and Piney M. Mineral Oil Metal Working Fluids (MWFs) - development of Practical Criteria for Mist Sampling. The Annals of Occupational Hygiene. 2000; 44(3): 165-172 (13) Chen MC, Shin TS, Lee WJ, Chang CC, and Tsai PJ. Concentration and

Particle Size Distribution of Oil Mist Exposed to Fastening Industry Workers. Journal of Occupational Safety and Health. 2006; 14(1): 8-16 (14) Rosenthal FS, and Yeagy BL. Characterization of metalworking fluid

aerosols in bearing grinding operations. AIHAJ : a journal for the science of occupational and environmental health and safety. 2001; 62(5):

379-382.

(15) Ross AS, Teschke K, Brauer M, and Kennedy SM. Determinants of exposure to metalworking fluid aerosol in small machine shops. The Annals of Occupational Hygiene. 2004; 48(5): 383-391.

(16) Thornburg J, and Leith D. Size distribution of mist generated during metal machining. Applied Occupational and Environmental Hygiene.

2000; 15(8): 618–628.

(17) Heitbrink WA, D’Arcy JB, and Yacher JM. Mist generation at machining center. American Industrial Hygiene Association Journal. 2000; 61:

22–30.

(18) Turchin H, and Byers P. Effect of oil contamination on metalworking fluid mist. Lubrication Engineering. 2000; 56(7): 21–25.

(19) Dasch JM, Ang CC, Mood M, and Knowles D. Variables affecting mist generation from metal removal fluids. Lubrication Engineering. 2002;

10–17.

(20) Michalek DJ, Hii WW, Sun J, Gunter KL, and Sutherland JW.

Experimental and analytical efforts to characterize cutting fluid mist formation and behavior in machining. Applied Occupational and Environmental Hygiene. 2003; 18: 842-854.

(21) Glaser R, Kurimo R, and Shulman S. Performance Testing of NIOSH Method 5524/ASTM Method D-7049-04, for Determination of Metalworking Fluids. Journal of Occupational and Environmental Hygiene. 2007; 4: 583–595.

(22) Sullivan PA, Eisen EA, Woskie SR, Kriebel D, Wegman DH, Hallock MF, Hammond SK, Tolbert PT, Smith TJ, and Monson RR. Mortality studies of metalworking fluid exposure in the automobile industry: VI. a case-control study of esophageal cancer. American Journal of Industrial Medicine. 1998; 34: 36-48.

(23) Koh D, Leow YH, and Goh CL. Occupational allergic contact dermatitis in Singapore. The Science of the Total Environment. 2001; 270: 97-101.

(24) Ueno S, Shiomi Y, and Yokota K. Metalworking fluid hand dermatitis.

Industrial Health. 2002; 40: 291-293.

(25) Oudyk J, Haines AT, and Arcy JD. Investigation respiratory responses to metalworking fluid exposure. Applied Occupational and Environmental Hygiene. 2003; 18: 939-946.

(26) Reeve GR, Stout AW, Hands D, and Curry E. Inpatient hospital admission rates for nonmalignant respiratory disease among workers exposed to metal removal fluids at a U.S. automobile manufacturer.

(27) Park D, Chin K, Kwag H, Youn K, Choi S, Ha K, Yoon C, and Yim S.

Effect of metalworking fluid mist exposure on cross-shift decrement in peak expiratory flow. Journal of Occupational Health. 2007; 49: 25-31.

(28) Verma DK. Relationships Between Inhalable, Thoracic, and Respirable Aerosols of Metalworking Fluids. Journal of Occupational and Environmental Hygiene. 2007; 4: 266–271.

(29) Russi M, Dubrow R, Flannery JT, Cullen MR, and Mayne ST.

Occupational exposure to machining fluids and laryngeal cancer risk:

contrasting results using two separate control groups. American Journal of Industrial Medicine. 1997; 31(2): 166-171.

(30) Robertson AS, Weir DC, and Burge PS. Occupational asthma due to oil mists. Thorax. 1988; 43: 200–205.

(31) Jarvholm B, Bake B, Lavenius B, Thiringer G, and Vokmann R.

Respiratory symptoms and lung function in oil mist-exposed workers.

Journal of Occupational Medicine. 1982; 24: 473-479.

(32) Massin N, Bohadana AB, Wild P, Goutet P, Kirstetter H, and Toamain JP.

Airway responsiveness, respiratory symptoms, and exposures to soluble oil mist in mechanical workers. Occupational and Environmental Medicine. 1996; 53(11): 748-752.

(33) Kennedy SM, Chan YM, Teschke K, and Karlen B. Change in airway responsiveness among apprentices exposed to metalworking fluids.

American Journal of Respiratory and Critical Care Medicine. 1999;

159(1): 87-93

(34) Cullen MR, Balmes JR, Robins JM, and Smith GJW. Lipoid pneumonia caused by oil mist exposure from a steel rolling tandem mill. American Journal of Industrial Medicine. 1981; 2:51-58

(35) Kazerouni N, Thomas TL, Petralia SA, and Hayes RB. Mortality among workers exposed to cutting oil mist: update of previous reports.

American Journal of Industrial Medicine. 2000; 38(4): 410-416.

(36) Mattsby-Baltzer I, Sandin M, Ahlstrom B, Allenmark S, Edebo M, Falsen E, K. Pedersen, Rodin N, Thompson RA, and Edebo L. Microbial Growth and Accumulation in Industrial Metal-Working Fluids. Applied and Environmental Microbiology. 1989; 55(10): 2681-2689.

(37) Dilger S, Fluri A, and Sonntag HG. Bacterial contamination of preserved and non-preserved metal working fluids. International Journal of Hygiene and Environmental Health. 2005; 208: 467–476.

(38) Park D, Teschke K, and Bartlett K. A model for predicting endotoxin concentrations in metalworking fluid sumps in small machine shop. The Annals of Occupational Hygiene. 2001; 45(7): 569-576.

(39) Simpson AT, Stear M, Groves JA, Piney M, Bradley SD, Stagg S, and Crook B. Occupational exposure to metalworking fluid mist and sump fluid contaminants. The Annals of Occupational Hygiene. 2003; 47(1):

17-30.

(40) Veillette M, Thorne PS, Gordon T, and Duchaine C. Six month tracking of microbial growth in a metalworking fluid after system cleaning and recharging. The Annals of Occupational Hygiene. 2004; 48(6): 541-546.

(41) Wang H, Reponen T, Lee SA, White E, and Grinshpun SA. Size distribution of airborne mist and endotoxin-containing particles in metalworking fluid environments. Journal of Occupational and Environmental Hygiene. 2007; 4: 157-165.

(42) Wang HX, Reponen T, Adhikari A, Willeke K, and Grinshpun SA. Effect of Fluid Type and Microbial Properties on the Aerosolization of Microorganisms from Metalworking Fluids. Aerosol Science and Technology. 2004; 38: 1139–1148.

(43) Chang SC, Rihana A, Bahrman S, Gruden CL, Khijniak AI, Skerlos SJ, and Adriaens P. Flow cytometric detection and quantification of mycobacteria in metalworking fluids. International Biodeterioration and

(44) Kreiss K, and Cox-Ganser J. Metalworking fluid-associated hypersensitivity pneumonitis: a workshop summary. American Journal of Industrial Medicine. 1997; 32: 423–432.

(45) Moore JS, Christensen M, Wilson RW, Wallace RJ, Jr. Zhang Y, Nash DR, and Shelton B. Mycobacterial contamination of metalworking fluids:

involvement of a possible new taxon of rapidly growing mycobacteria.

American Industrial Hygiene Association Journal. 2000; 61: 205–213.

(46) Bernstein DI, Lummus ZL, Santilli G, Siskosky J, and Bernstein, L.

Machine operator’s lung: a hypersensitivity pneumonitis disorder associated with exposure to metalworking fluid aerosols. Chest. 1995;

108: 636–641.

(47) Watt WD. Observations on the relationship between triazines and Mycrobacteria in metal removal fluids. Applied Occupational and Environmental Hygiene. 2003; 18: 961-965.

(48) Abrams L, Seixas N, Robins T, Burge H, Muilenberg M, and Franzblau A.

Characterization of metalworking fluid exposure indices for a study of acute respiratory effects. Applied Occupational and Environmental Hygiene. 2000; 15(6): 492-502.

(49) Rosenman KD, Reille MJ, and Kalinowski D. Work-related asthma and respiratory symptoms among workers exposed to metalworking fluids.

American Journal of Industrial Medicine. 1997; 32: 325–331.

(50) Alomar A. Occupational skin from cutting fluids. Dermatologic Clinics.

1994; 12(3): 537-546.

(51) Graves LA, Eisen EA, Smith TJ, Pothier LJ, Kriebel D, Woskie S, Kennedy SM, Shalat S, and Monson RR. Respiratory health of automobile workers exposed to metalworking fluids aerosols: respiratory symptoms. American Journal of Industrial Medicine. 1997; 32: 450–459.

(52) Penes MC, Vallon JJ, Sabot JF, and Vallon C. GC/MS detection of paraffins in a case of lipoid pneumonia following occupational exposure

to oil spray. Journal of Analytical Toxicology. 1990; 14:372-374.

(53) Chan-Yeung M, and Malo JL. Occupational asthma. The New England Journal of Medicine. 1995; 333(2):107-112.

(54) Mehta SK, Bell-Robinson DM, Groves TO, Stetzenbach LD, and Pierson DL. Evaluation of portable air samplers for monitoring airborne culturable bacteria. American Industrial Hygiene Association Journal.

2000; 61(6): 850-854.

(55) Lin X, Reponen TA, Willeke K, Grinshpun SA, Foarde KK, and Ensor DS. Long-term sampling of airborne bacteria and fungi into a non-evaporating liquid. Atmospheric Environment. 1999; 33: 4291-4298.

(56) 林雅晴。衝擊器之生物氣膠採樣效率。國立台灣大學公共衛生學院 環境衛生研究所，碩士論文。1998。

(57) SKC. Biosampler operating instructions.

(58) IOSH (行政院勞工委員會勞工安全衛生研究所) 養豬場生物氣膠暴 露危害研究(二)-細菌菌種分析與探討」，IOSH85-H302，1996。

(59) VALIDATION LIST N° 57. Int. J. Syst. Bacteriol. 1996; 46: 625-626.

(60) Washington W, Stephen A, William J, Elmer K, Gary P, Paul S, and Gail W. Koneman’s color atlas and textbook of diagnostic microbiology, sixth edition. Lippincott Williams & Wilkins. 2006.

(61) 蔡文城。實用臨床微生物診斷學，第六版。九州圖書文物有限公司，

1991。

(62) Sheehan MJ, and Hands D. Metalworking Fluid Mist—Strategies to Reduce Exposure: A Comparison of New and Old Transmission Case Transfer Lines. Journal of Occupational and Environmental Hygiene.

2007; 4: 288–300.