Folk medicine antibiotic and analgesic development of the first report of sperm Valley
Abstract
Heat drugs in general clinical medicine for the treatment of fever dysentery, carbuncle swollen, sore and so performance in heat. Relieving drugs have mitigation
Pain, fever, treatment of measles, chicken pox and other effects. This second class medicine from modern medicine point of view, roughly equivalent to antimicrobial
, Antipyretic and anti-inflammatory, analgesic. . . . Such as role. In this
study, antipyretic and relieving drugs to the principle of collection of 50 kinds of Chinese herbal medicines, do antibacterial and analgesic activity evaluation.
Assessment of sperm to the Valley in both the two herbs and meaningful role in one of the obvious; thus further explore the Valley of sperm
Extracts the divided parts of antibacterial, analgesic, sedative and nourish the liver and other physical activity, found that part of each division were
Antibacterial action, n-hexane and dichloromethane some have analgesic effects, and no inhibition of the central role, while the dichloro-A
Alkyl part of the hexane layer will have distinct liver.
Ethyl acetate extracts from the isolated valley sperm analgesic active ingredients: (Ⅰ) by the hexadecanoic acid, octa
decanoic acid, eicosanoic acid, docosanoic acid and hexacosamol, octacosa
nol, triacontanol formed by the mixture of long chain esters. (Ⅱ) dotriacotanoic acid, tetrac
ontanoic acid and hexacontanoic acid mixture (Ⅲ) 1 - heptacosanol (46.0
%), 1 - octacosanol (5.0%) and 1 - nonacosanol (49.0%) of the mixture , (Ⅴ) Stigmasterol ((77.0%) and β-sitosterol (23.0%) of the mixture , (Ⅵ) triglyceride,(Ⅶ) 1 - hexacosanol (42.6%), 1 - octacosano
l 1 - octacosanol (41.9%) and 1 - triacotanol (15.5%) of the mixture, (Ⅶ) semi - vioxanthin, (Ⅸ) homoplantaginin.
Component (Ⅶ) also antibacterial active ingredients, its minimum inhibitory concentration Staphylococcus aureus18
ug / ml, against Staphylococcus epidermidisto 20 gu / ml, 4 on Sa llus subtilis
ug / ml, against Bacillus cereus was 8ug / ml, on Micrococcus leteus to 20ug / ml, on
Pseudomonas aeruginosa is 18 ug / ml.
The physical activity assessment in this study isolated the active ingredient with proven Valley sperm do have antibiotics and analgesic efficacy, as
Should be developed in clinical medicine.
English Abstract
