Dengue pathogenesis research and teaching

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國立成功大學「邁向頂尖大學計畫」

  延攬優秀人才工作報告表

NCKU’s “Aim for the Top University Project”

Work Report Form for Distinguished Scholars

■續聘

continuation of employment

□離職

resignation

100 年 7 月 13 日更新

受聘者姓名

Name of the Employee RobertAnderson 男 女Male Female

聘　期 Period of Employment From 2014 年(y) 06 月(m) 23 日(d) to 2014 年(y) 07 月(m) 31 日(d) 研究或教學或科技研發與管理計畫名稱 The project title of research,

teaching, technology development and management

Dengue pathogenesis research and teaching 計畫主持人（申請單位主管） Project Investigator (Head of Department/Center) Dr Yee-Shin Lin 補助延聘編號

Grant Number

HUA103-21T-22-238

一、

研究、教學、科技研發與管理工作全程經過概述。（由受聘人填寫）

Please summarize the entire research, teaching, or science and technology R&D and management work process (To be completed

by the employee)

For this 5 week period (June 23-July 31 2014) I was involved primarily in ongoing collaborative research with Dr. Yee-Shin Lin as well as graduate student MSc and PhD Defense examinations, specifically:

Collaborative research. I am involved in co-advising several ongoing research projects together with Dr. Y-S Lin.

These activities have resulted in the completion or preparation of the following manuscripts and/or presentations: 1. Wan, S.-W., Lu, Y.-T., Huang, C.-H., Lin, C.-F., Liu, H.-S., Yeh, T.-M., Anderson, R., Yen, Y.-T., Wu-Hsieh, B.A. and Lin, Y.-S. (2014) Protection against dengue virus infection in mice by administration of antibodies against C-terminal modified nonstructural protein-1. PLoS One 9, e92495

2. Ho, T.-S., Lin, C.-F., Liu, C.-C., Yeh, T.-M., Anderson, R. and Lin, Y.-S. Lessons learned from dengue - Focus on Taiwan in " Dengue fever: transmission, diagnosis & surveillance", J. Whitehorn and J. Farrar, eds, Future Medicine, Clinical Insights ebook, pp. 49-64, 2014.

3. Lu, S.-L, Kuo, C.-F., Chen, H.-W., Wu, J.-J., Liu, C.-C., Anderson, R. and Lin, Y.-S. Defective acidification of group A streptococcus-containing autophagosomes facilitates bacterial survival and growth in endothelial cells. BMC Microbiology, submitted.

4. Fang, Y.-T., Wan, S.-W., Lu, Y.-T., Yao, J.-H., Lin, C.-F., Hsu, L.-J., Brown, M.G., Marshall, J.S., Anderson, R. and Lin, Y.-S. Autophagy facilitates antibody-enhanced dengue virus infection of human pre-basophil/Mast cells. PLoS One, minor revision.

5. Anderson, R. Roles of mast cells in dengue virus disease. Invited seminar, Tzu-Chi University, Hualien, July 8 2014.

Graduate student supervision and thesis examination:

1. Chen, Chin-Yu MSc thesis defense examiner July 4 2014 2. Chen, Pei-Wei MSc thesis defense examiner July 4 2014 3. Lu, Shiou-Ling PhD thesis defense examiner July 10 2014 4. Lin, Jessica MSc thesis defense examiner July 11 2014 5. Lee, Han MSc thesis defense examiner July 30 2014

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二、研究或教學或科技研發與管理成效評估（由計畫主持人或單位主管填寫）

Please evaluate the performance of research, teaching or science and technology R&D and management Work: ( To be completed

by Project Investigator or Head of Department/Center)

(1)是否達到延攬預期目標？

Has the expected goal of recruitment been achieved?

本次來訪以在研究上的討論及參加碩博士班畢業論文口試為主，共計參加五場口試，修改學

生論文，並討論 paper submission，成效符合預期目標。

(2)研究或教學或科技研發與管理的方法、專業知識及進度如何？

What are the methods, professional knowledge, and progress of the research, teaching, or R&D and management work?

在研究上，主要研究主題為登革病毒以及 A 群鏈球菌之致病機制。2014 年已發表一篇期刊論

文，以及應邀撰寫 Dengue e-Book chapter，以 Focus on Taiwan 為主題，分享台灣經驗。另有

一篇期刊論文已進行修改目前是第二次的 minor revision，還有在投稿中的 manuscript。在指導

學生上，本次來訪共計參加五場碩博士班畢業論文口試，與學生進行討論並修改論文。

(3)受延攬人之研究或教學或科技研發與管理成果對該計畫(或貴單位)助益如何？

How have the research, teaching, or R&D and management results of the employed person given benefit to the project (or your unit)?

此密切的國際合作在傳染性疾病及訊息研究中心的登革病毒、細菌、及訊息傳遞研究有很大的

助益。參加博士班和碩士班研究生畢業論文口試，提供精闢的見解。對於研究生無論在研究上

以及英文寫作和口語能力的增強都提供極大助益，並且共同發表論文。

(4)受延攬人於補助期間對貴單位或國內相關學術科技領域助益如何？

How has the employed person, during his or her term of employment, benefited your unit or the relevant domestic academic field?

Dr. Robert Anderson 對於成大碩博士班研究生在學術研究上提供貢獻，擔任研究生的論文指

導委員，並且參加論文口試。本次並應邀在慈濟大學進行專題演講，講題為 ”Roles of mast

cells in dengue virus disease”。

(5)具體工作績效或研究或教學或科技研發與管理成果：

Please describe the specific work performance, or the results of research, teaching, or R&D and management work:

1. 共同合作探討登革病毒以及 A 群鏈球菌之致病機制，對於登革疫苗研發提供策略。

2. 共同發表期刊論文以及 book chapter，並有 manuscripts 在送審或撰寫中。

3. 英文論文寫作的輔導。

4. 參加五場碩博士班畢業論文口試。

(6)是否續聘受聘人? Will you continue hiring the employed person?

▓續聘

Yes □不續聘No ※此報告表篇幅以三～四頁為原則。This report form should be limited to 3-4 pages in principle.

※此表格可上延攬優秀人才成果報告繳交說明網頁下載。

This report form can be downloaded in http://scholar.lib.ncku.edu.tw/explain/