• 沒有找到結果。

Mining correlations of human gene expression from digital gene expression profiles

N/A
N/A
Protected

Academic year: 2022

Share "Mining correlations of human gene expression from digital gene expression profiles"

Copied!
1
0
0

加載中.... (立即查看全文)

全文

(1)

題名: Mining correlations of human gene expression from digital gene expression profiles

作者: J. T. Horng;H. D. Huang;K. Y. Tseng;T. S. Tsou;B. J. Liu 貢獻者: Department of Bioinformatics

關鍵詞: gene expression;data mining;EST;SAGE;UniGene 日期: 2003-11

上傳時間: 2010-03-19T08:24:23Z 出版者: Asia University

摘要: The study addressed here aimed to analyze a large number of human genome transcripts from diverse tissues and to discover genes that with similar expression profiles in different human tissues. These genes may be of potential biological or pharmaceutical relevance. We propose an approach to discover the correlations of tissue gene expression by analyzing digital gene expression profiles of different human tissues. A simple statistical test was used to correlate genes having similar expression profiles. We used the information of tissue gene expression to discover the correlations of expressed genes. The correlations of gene expression revealed that such genes were specifically expressed in particular tissues with similar expression profiles and could be used to identify the relationships of the genes that be co-regulated, involved in the same biochemical pathway and signal transduction process.

參考文獻

相關文件

The ratio of relative ASS expression (expressed as the ASS/ β -actin ratio) in tumor tissues to that in normal tissues was correlated with large tumor size (P=0.007) and with the

Furthermore, the synchronous alterations in expression profiles of the module member genes (transcripts) imply high-level regulatory coordination, which dictates both gene

Based on miRNA and annotated gene expression profiles, the term “coTFBS” was introduced to detect common transcription factors and the corresponding binding sites within the

The gene array for 96 genes associated with members of human matrix metalloproteinases (MMPs) and adhesion molecules revealed that the expression of MMP-2, -3, -10, and -24 genes

Our aim was to clarify whether statins could inhibit the replication of cyto- megalovirus (CMV) in human cells and to determine the changes in gene expression profiles in host

The normal tissues show homogenous expression pattern in liver cells in comparison with the heterogeneous expression feature of HCC cells which includes expressed and decreased

co-regulated genes in a biological process may show a periodic pattern in their cell cycle expression, we also should group genes with periodic similar patterns over multiple

It was previously shown that the fumA and fumC genes are most highly expressed during aerobic con- ditions [5], whereas the fumB gene was expressed at a higher level under