[PDF] Top 20 Liver Development and Cancer Formation in Zebrafish
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Liver Development and Cancer Formation in Zebrafish
... p53 and Rb (Murakami et al., 1991), and AXIN1 (Satoh et ...involved in hepatocarcinogenesis, primarily via genomic instability and changes in epigenetic status, as well as gene ... See full document
16
Liver-Specific Expressions of HBx and src in the p53 Mutant Trigger Hepatocarcinogenesis in Zebrafish
... pathways and facilitate HCC formation. In the HBx-induced HCC mouse model in which HBx was driven by the albumin promoter, all of the four lines of HBx transgenic mouse developed HCC at ... See full document
19
Treatment with Myf5-morpholino results in somite patterning and brain formation defects in zebrafish
... scripts in neurons, but their biological roles during neurogenesis remain ...unclear. In this study, we observed that brain development was impeded in myf5-MO-treated ...the zebrafish ... See full document
10
Hepatitis B virus X antigen and aflatoxin B1 synergistically cause hepatitis, steatosis and liver hyperplasia in transgenic zebrafish
... protein and contained increased levels of glycogen (Zhu et ...rate and tumor volume doubling time in humans (Kitamura et ...1993). In this study, both HBx transgenic fish treated with AFB1 ... See full document
12
Thioacetamide induced liver damage in zebrafish embryo as a disease model for steatohepatitis
... tance and oxidative stress have critical roles in the pathogenesis of fatty liver ...of formation steatohpatitis and it is a good platform for the drug screening that leads to drug ... See full document
8
LPA1 is essential for lymphatic vessel development in zebrafish
... role in vascular formation, we identified an lpa 1 gene in ze- brafish, which is a well-established model for angiogen- esis research (31, ...results in inhibition of thoracic duct ... See full document
10
Molecular Mechanisms of Apoptosis Induced by Magnolol in Colon and Liver Cancer Cells
... Involved in Magnolol-Induced Caspase Activation To study further the effect of elevated [Ca 2 ] i on the development of apoptosis, Hep G2 cells were pretreated with 20 mM U73122 (a phospholipase C ... See full document
11
Phosphatidylserine receptor is required for the engulfment of dead apoptotic cells and for normal embryonic development in zebrafish
... library, and designed PSR morpholinos for the knockdown of PSR expression during the embryonic development of ...accumulated in the furrow or individual boundary of the whole somite, and ... See full document
11
The toxic effect of Amiodarone on valve formation in the developing heart of zebrafish embryos
... forces and stimulates endocardial cells to rearrange and change the genetic expression profiles ...flow and whether such slower blood flow is common to other antiarrhythmic drugs, we observed and ... See full document
12
Systemic Study on Association between Dioxin and Liver Cancer.
... I222 and D247, which are classified in the outlier ...1 and Group 2 in the ’150 loop’ (i.e. residue 147-152), in which the ‘150-cavity’ is adjacent to the active site ...ligands ... See full document
32
Systemic Study on Association between Dioxin and Liver Cancer.
... Pubmed and Medline for reports published in journals in English using key words limited to 2,3,7,8-tetrachlorodibenzo-p-dioxin, TCDD, human exposure, liver cancer, liver ... See full document
1
In vitro and in vivo study of phloretin-induced apoptosis in human liver cancer cells involving inhibition of type II glucose transporter
... shown in Figure 4d, treatment of HepG2 cells with 20 lM cytochalasin B did not activate caspases or apoptotic regulatory ...8 and 9, along with increased expression of p53 protein, translocation of Bax from ... See full document
10
Positive Feedback Regulation between IL10 and EGFR Promotes Lung Cancer Formation
... cytokine, in the tumorigenesis of various cancer types is ...measured in lung tumor tissues and serum, both of which were from human and lung cancer transgenic mice (EGFR L858R ... See full document
8
In-situ Formation and Assembly of Gold Nanoparticles by Gum Arabic as Efficient Photothermal Agent for Killing Cancer Cells
... pattern in Figure 4b shows the major accumulation of Au-SNPs@GA in the liver and that the highest value is observed from four hours to six days after ...60% in the liver, which ... See full document
7
Allicin Induces p53-Mediated Autophagy in Hep G2 Human Liver Cancer Cells
... autophagosomes and mitochondria was examined by LC3-II– FITC punctate formation and MitoTracker-Red ...punctate formation and colocalized with mitochondria (Figure ...the ... See full document
17
Molecular Mechanisms in Apoptosis Induced by Magnolol in Colon and Liver Cancer Cells
... activation and reduced the occurrence of ...seen in Hep G2 cells and that [Ca(2+)](i), Cyto c, and Fas function as intracellular signals to coordinate those ... See full document
1
Egr1 gene knockdown affects embryonic ocular development in zebrafish
... changes in zebrafish embryonic ocular development after early growth response factor 1 (Egr1) gene knockdown by Egr1-specific translation inhibitor, morpholino oligonucleotides ...celled ... See full document
9
Complexity of cis-regulatory organization of six3a during forebrain and eye development in zebrafish
... Conclusions In this study, we identified two enhancers in the regula- tion of zebrafish ...ments in both modules demonstrated that the multiple elements in module A work synergistically ... See full document
18
Fagigue Patterns and Correlates in Male Liver Cancer Patients Receiving Transcatheter Hepatic Arterial Chemoembolization
... ANOVA and GEE together, several important issues became ...change in fatigue over time was sig- nificant as analyzed by repeated measures ANOVA, time was not found to be significant in the GEE ... See full document
7
Fatigue Patterns and Correlates in Male Liver Cancer Patients Receiving Transcatheter Hepatic Arterial Chemoemobilization
... USA. Liver cancer is a leading cancer in Taiwan, especially in ...changes in fatigue, symptom distress, anxiety and depression in cancer patients across four ... See full document
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