第六章 結論與建議
6.2 建議
混合毒性牽涉的因素非常複雜,除了毒化物本身在生物體分子作用的 位置不同,毒化物間的化學反應、毒化物的降解、毒化物和環境間的反應、
毒化物受生物體內生化系統酵素影響的化學反應,都是會造成複雜毒性效 應的原因,未來在進行混合毒性的探討,應當納入更多可能造成複雜毒性 效應之反應的考量,以免錯估混合毒性在環境中的風險。
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洪東榮. 中國醫藥大學附設醫院毒物科暨毒藥物諮詢檢驗中心網站-氰化 物中毒的診斷與救治. 網址:
http://www.cmuh.cmu.edu.tw/cmuh/introduction/layout_2/?did=10124&id
=867
附錄一 單一毒性原始數據
Formaldehyde
Conc Initial light Final light
(mg/L)
Conc Initial light Final light
(mg/L)
Conc Initial light Final light
(mg/L)
Conc Initial light Final light
(mg/L)
Formaldehyde
Conc Initial light Final light
(mg/L)
Conc Initial light Final light
(mg/L)
Conc Initial light Final light
(mg/L)
Conc Initial light Final light
(mg/L)
Conc Initial light Final light
(mg/L)
Conc Initial light Final light
(mg/L)
Glutaraldehyde
Conc Initial light Final light
(mg/L)
Conc Initial light Final light
(mg/L)
Conc Initial light Final light
(mg/L)
Conc Initial light Final light
(mg/L)
Conc Initial light Final light
(mg/L)
Conc Initial light Final light
(mg/L)
Acetonitrile
Conc Initial light Final light
(mg/L)
Conc Initial light Final light
(mg/L)
Conc Initial light Final light
(mg/L)
Conc Initial light Final light
(mg/L)
Conc Initial light Final light
(mg/L)
Conc Initial light Final light
(mg/L)
3-Chloroaniline
Conc Initial light Final light
(mg/L)
Conc Initial light Final light
(mg/L)
Conc Initial light Final light
(mg/L)
Conc Initial light Final light
(mg/L)
Conc Initial light Final light
(mg/L)
Conc Initial light Final light
(mg/L)
3-Chloroaniline
Conc Initial light Final light
(mg/L)
Conc Initial light Final light
(mg/L)
Conc Initial light Final light
(mg/L)
Conc Initial light Final light
(mg/L)
Conc Initial light Final light
(mg/L)
Conc Initial light Final light
(mg/L)
4-Chloroaniline
Conc Initial light Final light
(mg/L)
Conc Initial light Final light
(mg/L)
Conc Initial light Final light
(mg/L)
Conc Initial light Final light
(mg/L)
Conc Initial light Final light
(mg/L)
Conc Initial light Final light
(mg/L)
2,5-Dichloroaniline
Conc Initial light Final light
(mg/L)
Conc Initial light Final light
(mg/L)
Conc Initial light Final light
(mg/L)
Conc Initial light Final light
(mg/L)
Conc Initial light Final light
(mg/L)
Conc Initial light Final light
(mg/L)
3,4-Dichloroaniline
Conc Initial light Final light
(mg/L)
Conc Initial light Final light
(mg/L)
Conc Initial light Final light
(mg/L)
Conc Initial light Final light
(mg/L)
Conc Initial light Final light
(mg/L)
Conc Initial light Final light
(mg/L)
2-Bromoaniline
Conc Initial light Final light
(mg/L)
Conc Initial light Final light
(mg/L)
Conc Initial light Final light
(mg/L)
Conc Initial light Final light
(mg/L)
附錄二 混合毒性原始數據
Formaldehyde+3-Chloroaniline (TU= 1:1)
TU Initial light Final light Control 103.05 85.88
TU Initial light Final light
Control 94.79 76.39
TU Initial light Final light
Control 92.33 83.28
TU Initial light Final light
Control 94.76 84.46
Formaldehyde+4-Chloroaniline (TU= 1:1)
TU Initial light Final light
Control 99.65 86.86
TU Initial light Final light
Control 91.95 84.97
TU Initial light Final light
Control 96.23 91.11
TU Initial light Final light
Control 98.5 94.75
TU Initial light Final light
Control 98.69 98.02
TU Initial light Final light
Control 97.64 91.19
Glutaraldehyde +3-Chloroaniline (TU= 1:1)
TU Initial light Final light
Control 89.48 79.64
Glutaraldehyde +3-Chloroaniline (TU= 1:1)
TU Initial light Final light
Control 90.8 73.83
Glutaraldehyde +3-Chloroaniline (TU= 1:1)
TU Initial light Final light
Control 94.68 90.51
Glutaraldehyde +4-Chloroaniline (TU= 1:1)
TU Initial light Final light
Control 97.69 89.36
Glutaraldehyde +4-Chloroaniline (TU= 1:1)
TU Initial light Final light
Control 91.55 72.47
Glutaraldehyde +4-Chloroaniline (TU= 1:1)
TU Initial light Final light Control 102.01 80.4
Glutaraldehyde +4-Chloroaniline (TU= 1:1)
TU Initial light Final light
Control 100.5 97.5
Glutaraldehyde +2,4-Dichloroaniline (TU= 1:1)
TU Initial light Final light
Control 91.44 84.96
Glutaraldehyde +2,4-Dichloroaniline (TU= 1:1)
TU Initial light Final light
Control 99.21 93.47
Glutaraldehyde +2,5-Dichloroaniline (TU= 1:1)
TU Initial light Final light
Control 97.18 94.97
Glutaraldehyde +2,6-Dichloroaniline (TU= 1:1)
TU Initial light Final light
Control 91.44 87.94
Glutaraldehyde +2,6-Dichloroaniline (TU= 1:1)
TU Initial light Final light Control 100.34 100.33
Glutaraldehyde +3,4-Dichloroaniline (TU= 1:1)
TU Initial light Final light
Control 86.87 73.55
Glutaraldehyde +3,4-Dichloroaniline (TU= 1:1)
TU Initial light Final light Control 102.86 91.36
Glutaraldehyde +3,4-Dichloroaniline (TU= 1:1)
TU Initial light Final light
Control 98.74 87.19
Glutaraldehyde +3,5-Dichloroaniline (TU= 1:1)
TU Initial light Final light
Control 96.21 89.59
Glutaraldehyde +2-Bromoaniline (TU= 1:1)
TU Initial light Final light Control 103.46 91.57
Glutaraldehyde +2-Bromoaniline (TU= 1:1)
TU Initial light Final light
Control 96.1 93.47
Glutaraldehyde +2-Bromoaniline (TU= 1:1)
TU Initial light Final light
Control 91.81 79.46
Propionaldehyde +3-Chloroaniline (TU= 1:1)
TU Initial light Final light
Control 91.94 87.89
Propionaldehyde +3-Chloroaniline (TU= 1:1)
TU Initial light Final light
Control 95.63 82.78
Propionaldehyde +4-Chloroaniline (TU= 1:1)
TU Initial light Final light
Control 89.02 80.71
Propionaldehyde +3,4-Dichloroaniline
(TU= 1:1)
TU Initial light Final light
Control 92.73 77.84
Butyraldehyde +2,4-Dichloroaniline (TU= 1:1)
TU Initial light Final light
Control 95.82 92.14
Butyraldehyde +2,5-Dichloroaniline (TU= 1:1)
TU Initial light Final light
Control 91.72 77.32
Butyraldehyde +2-Bromoaniline (TU= 1:1)
TU Initial light Final light
Control 96.16 90.36
Acetonitrile +3-Chloroaniline (TU= 1:1)
TU Initial light Final light
Control 94.8 86.51
Acetonitrile +4-Chloroaniline (TU= 1:1)
TU Initial light Final light Control 102.53 87.83
Acetonitrile +2,4-Dichloroaniline (TU= 1:1)
TU Initial light Final light
Control 102 89.04
Acetonitrile +2-Bromoaniline (TU= 1:1)
TU Initial light Final light
Control 89.76 91.6
Malononitrile +3-Chloroaniline (TU= 1:1)
TU Initial light Final light
Control 96.86 91.85
Malononitrile +4-Chloroaniline (TU= 1:1)
TU Initial light Final light
Control 95.15 92.27
Malononitrile +2,4-Dichloroaniline (TU= 1:1)
TU Initial light Final light
Control 97.57 96.12
Malononitrile +2,6-Dichloroaniline (TU= 1:1)
TU Initial light Final light Control 100.68 93.38
附錄三 HPLC分析之檢量線
4-Chloroaniline 之 HPLC 檢量線
y = 135323x + 276086 R2 = 0.9992
0.E+00 5.E+06 1.E+07 2.E+07
0 20 40 60 80 100 120
4-Chloroaniline 濃度 (mg/L)