第五章 討論與結論
第七節 臨床應用
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cytokines）IL-6與腫瘤壞死因子（tumor necrosis factor），與憂鬱症患者身上所 發現的促炎性細胞因子IL-1、IL-6以及干擾素（interferons）相似（Chen et al., 2013）。此前瞻性議題亦為後續研究可予以探討的議題，而由本研究所得的結 果也提醒後續研究者需注意，並釐清促炎性細胞因子影響是否造成嗜睡症狀，
進一步影響憂鬱情緒。
第七節 臨床應用
本研究在於提醒臨床工作者對 OSA 患者進行憂鬱症臨床診斷時，需注意 與釐清 OSA 患者是否以白天嗜睡的情況，來回應憂鬱症狀相關的嗜睡表現，以 降低誤判 OSA 患者憂鬱情緒的可能性。
過去研究者指出 OSA 患者（每人 C$118）在憂鬱症診斷下所花費的醫療 費用比一般大眾（每人 C$224）來的低，卻在抗鬱劑上所花費的費用比一般大 眾來得高（OSA 患者：C$324.76、一般大眾：C$232.21），研究者將此現象解 釋為一般大眾較傾向於以參與心理治療的方式進行治療，而 OSA 患者嗜睡的情 況則可能影響心理治療取向的參與而採取藥物治療的方式（Smith et al., 2002）。
上述研究結果說明了，相對於一般大眾，OSA 患者更常使用藥物治療，而本研 究認為 OSA 患者使用在抗憂鬱劑上的花費較高，另一可能性來自於 OSA 患者 憂鬱症診斷被高估所致，此現象亦可能使得抗憂鬱劑的效果被降低。因此，釐 清 OSA 患者是否以白天嗜睡的情況，來回應憂鬱症狀相關的嗜睡表現，以降低 誤判 OSA 患者憂鬱情緒的可能性，亦會降低醫療成本。
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