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Effects of aerobic exercise combined with dual-task training on cognitive functions in patients with cognitive impairment

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ADI 2013 Abstract Submission

Non-Pharmacological Interventions

ADI13-1159

EFFECTS OF AEROBIC EXERCISE COMBINED WITH DUAL-TASK TRAINING ON COGNITIVE FUNCTIONS IN PATIENTS WITH COGNITIVE IMPAIRMENT

Y.-H. Chu 1,*, P.-F. Tang 2, 3, 4, M.-J. Chiu 3, 5, Y.-C. Lin 6, T.-F. Chen 5

1Department of Physical Therapy, China Medical University, Taichung,2School and Graduate Institute of Physical

Therapy, College of Medicine,3Graduate Institute of Brain and Mind Sciences, College of Medicine, National Taiwan

University,4Department of Physical Medicine and Rehabilitation,5Department of Neurology, National Taiwan University

Hospital and National Taiwan University College of Medicine, Taipei,6Department of Physical Medicine and

Rehabilitation, China Medical University Hospital, Taichung, Taiwan

Presentation Method - Preference: Poster only

Do you give permission for your accepted abstract to be published on the ADI conference website?: No If your abstract is accepted for oral presentation at the conference, would you allow your PowerPoint presentation to be on the ADI website after the conference?: No

Are you submitting a scientific or non scientific abstract?: Scientific

Objectives: Effects of aerobic exercise combined with dual-task training on cognitive functions in patients with cognitive

impairment are unclear. The aim of the study was to investigate the effects of a 3-month moderate intensity aerobic exercises combined dual-task training on cognitive functions in patients with cognitive impairment.

Methods: Twenty patients with mild cognitive impairment (MCI) or mild Alzheimer’s disease (AD) (age: 61–88 years)

participated in the randomized controlled trial and were randomly allocated to the aerobic exercise combined dual-task training group (aerobic group) or the stretch control group (stretch group). The both groups received health education and exercises training for 12 weeks. The aerobic group received three 90-minuate group exercises sessions, that included aerobic exercises combined with dual-task training, and two 30-minute individual walking exercise sessions at home per week. The stretch group received three 90-minuate group exercise sessions that included stretch exercises and activities in sitting per week. Both groups received examinations on cognitive functions at baseline, post-training and after a 3-month follow-up period.

Results: There were no differences in the cognitive functions between the groups at baseline. After 3 months of training,

the aerobic group showed a significant increase scores in the logical memory–immediate recall (P < 0.05) and the stretch group showed a significant increase scores in visual reproduction–immediate recall (P < 0.05). Both groups maintained cognitive functions at follow-up period. In addition, the aerobic group showed better performance of Modified Card Sorting Test than stretch group after 3 months of training and higher score of Mini-Mental State Examination and logical

memory–delay recall at the 3-month follow-up period than the stretch group.

Conclusion: Both aerobic exercise combined dual-task training and stretch exercise training were effective in improving

memory function of patients with MCI and mild AD. Aerobic exercise combined dual-task training especially produced cognitive benefit at follow-up period.

References: Olazarán, J., Muniz, R., Reisberg, B., Pena-Casanova, J., del Ser, T., Cruz-Jentoft, A.J., et al. 2004.

Benefits of cognitive-motor intervention in MCI and mild to moderate Alzheimer disease. Neurology. 63, 2348-2353. Schwenk, M., Zieschang, T., Oster, P., Hauer, K. 2010. Dual-task performances can be improved in patients with dementia: a randomized controlled trial. Neurology. 74, 1961-1968.

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