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[PDF] Top 20 HDAC Inhibition Decreases the Expression of EGFR in Colorectal Cancer Cells

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HDAC Inhibition Decreases the Expression of EGFR in Colorectal Cancer Cells

HDAC Inhibition Decreases the Expression of EGFR in Colorectal Cancer Cells

... Order of Authors: Chia-Wei Chou;Ming-Shiang Wu;Wei-Chien Huang;Ching-Chow Chen Abstract: Epidermal growth factor receptor (EGFR), a receptor tyrosine kinase which promotes cell proliferation and survival, ... See full document

48

Trichostatin A suppresses EGFR expression through induction of microRNA-7 in an HDAC-independent manner in lapatinib-treated cells

Trichostatin A suppresses EGFR expression through induction of microRNA-7 in an HDAC-independent manner in lapatinib-treated cells

... metabolisms in primary rat hepatocytes[47]. In contrast to inducing microRNA expression, TSA was also found to suppress miR-106b-93-25 cluster expression to inhibit proliferation and induce ... See full document

21

Regulations of Apoptosis by Epidermal Growth Factor and Its Signal  Transduction Inhibitors in Human Colorectal Cancer Cells

Regulations of Apoptosis by Epidermal Growth Factor and Its Signal Transduction Inhibitors in Human Colorectal Cancer Cells

... III the medium of the EGF group was higher than that of the DMSO group (p < ...among the EGF, EGF + EGF antibody and EGF + tyrphostin 51 groups. The expression ... See full document

2

TrichostatinA Suppresses EGFR Expression through Induction of MicroRNA-7 in an HDAC-Independent Manner in Lapatinib-Treated Cells

TrichostatinA Suppresses EGFR Expression through Induction of MicroRNA-7 in an HDAC-Independent Manner in Lapatinib-Treated Cells

... dual EGFR/HER2 tyrosine kinase inhibitor, has been shown to improve the survival rate of patients with advanced HER2-positive breast ...However, the off-target activity of lapatinib ... See full document

1

Expression of Survivin and p53 Modulates Honokiol-Induced Apoptosis in Colorectal Cancer Cells

Expression of Survivin and p53 Modulates Honokiol-Induced Apoptosis in Colorectal Cancer Cells

... However, the precise mechanism of honokiol-induced apoptosis in human colorectal cancer remains ...unclear. Colorectal cancer is one of the leading causes ... See full document

12

EGFR/SGLT1Interaction Does Not Respond to EGFR Modulators, But Inhibition of SGLT1 Sensitizes Prostate Cancer Cells to EGFR Tyrosine Kinase Inhibitors

EGFR/SGLT1Interaction Does Not Respond to EGFR Modulators, But Inhibition of SGLT1 Sensitizes Prostate Cancer Cells to EGFR Tyrosine Kinase Inhibitors

... bands in the Western blot of Figure ...between the linked representative group from triplicate experiments. Fig. 3. EGFR-SGLT1 interaction is irresponsive to modulators of ... See full document

21

Study on the effects of scutellarein decrease the proliferation through the EGFR inhibition of human lung cancer line A549

Study on the effects of scutellarein decrease the proliferation through the EGFR inhibition of human lung cancer line A549

... lung cancer cell line A549 has a strong ability in ...hyperplasia in the cells, highly expression is one of the major ...activity. In this work, we screened ... See full document

1

Demethoxycurcumin-induced DNA Damage Decreases DNA Repair-associated Protein Expression Levels in NCI-H460 Human Lung Cancer Cells.

Demethoxycurcumin-induced DNA Damage Decreases DNA Repair-associated Protein Expression Levels in NCI-H460 Human Lung Cancer Cells.

... Detection of etoposide resistance by measuring DNA damage in individual Chinese hamster ...Natl Cancer Inst 82: 779-783, ...colon cancer cells as quantitated by a sensitive HPLC assay ... See full document

1

Cantharidin induces G2/M phase arrest and apoptosis in human colorectal cancer colo 205 cells through inhibition of CDK1 activity and caspase-dependent signaling pathways

Cantharidin induces G2/M phase arrest and apoptosis in human colorectal cancer colo 205 cells through inhibition of CDK1 activity and caspase-dependent signaling pathways

... 2 expression in human bladder carcinoma cell ...growth inhibition was not mitigated in pancreatic cancer cells with NAC ...(8). In our study, CTD induce apoptosis can ... See full document

28

Pim kinase inhibitors possess anticancer properties through downregulation of EGFR family in HER2-positive cancer cells

Pim kinase inhibitors possess anticancer properties through downregulation of EGFR family in HER2-positive cancer cells

... site in moloney murine leukemia virus (PIM) proteins family, including PIM1, PIM2, PIM3, are serine/threonine kinases and promote cell growth, proliferation and drug ...overexpressed in many cancer ... See full document

1

p38α MAPK Mediates 17β-Estradiol Inhibition of MMP-2 and -9 Expression and Cell Migration in Human LoVo Colon Cancer Cells

p38α MAPK Mediates 17β-Estradiol Inhibition of MMP-2 and -9 Expression and Cell Migration in Human LoVo Colon Cancer Cells

... Division of Colorectal Surgery, Mackay Memorial Hospital, Taipei Abstract Epidemiological studies demonstrate that the incidence and mortality rates of colorectal cancer ... See full document

1

Justicidin A decreases the level of cytosolic Ku70 leading to apoptosis in human colorectal cancer cells.

Justicidin A decreases the level of cytosolic Ku70 leading to apoptosis in human colorectal cancer cells.

... a725@mail.ncku.edu.tw The natural product justicidin A, an arylnaphthalide lignan isolated from Justicia procumbens, significantly inhibited the growth of human colorectal cancer ... See full document

15

The depletion of securin enhances butein-induced apoptosis and tumor inhibition in human colorectal cancer

The depletion of securin enhances butein-induced apoptosis and tumor inhibition in human colorectal cancer

... induction in human colorectal cancer ...reduced the securin protein levels but conversely increased the phospho-histone H3 proteins, mitotic arrest and abnormal chromosomes segregation ... See full document

10

Theanaphthoquinone inhibits fatty acid synthase expression in EGF-stimulated human breast cancer cells via the regulation of EGFR/ErbB-2 signaling

Theanaphthoquinone inhibits fatty acid synthase expression in EGF-stimulated human breast cancer cells via the regulation of EGFR/ErbB-2 signaling

... Meng-Shih Weng; Chi-Tang Ho; Yuan-Soon Ho; Jen-Kun Lin 貢獻者:醫學檢驗暨生物技術學系 上傳時間:2009-08-25T02:39:09Z 摘要:Fatty acid synthase (FAS) is a major lipogenic enzyme catalyzing the synthesis of long-chain saturated ... See full document

2

Thrombin induces nestin expression via the transactivation of EGFR signalings in rat vascular smooth muscle cells

Thrombin induces nestin expression via the transactivation of EGFR signalings in rat vascular smooth muscle cells

... Department of Chemistry, National Taiwan University, Taipei 106, Taiwan Received 22 August 2006; revised 18 October 2006; accepted 25 October 2006 Available online 13 November 2006 Abstract—Sodium ...catalyzed ... See full document

3

Baicalein Activates Aryl Hydrocarbon Receptor and Decreases the Expression of CDK4 and Cyclin D1 to Induce G1 Phase Arrest in Oral Cancer Cells

Baicalein Activates Aryl Hydrocarbon Receptor and Decreases the Expression of CDK4 and Cyclin D1 to Induce G1 Phase Arrest in Oral Cancer Cells

... and Decreases the Expression of CDK4 and Cyclin D1 to Induce G1 Phase Arrest in Oral Cancer Cells Ya-Hsin Cheng 1 , Lih-Ann Li 2 , Pinpin Lin 2 , Li-Chuan Cheng 2 , and ... See full document

1

The Management of Hepatic Metastasis in Colorectal Cancer

The Management of Hepatic Metastasis in Colorectal Cancer

... administered in combination with chemotherapy for the neoadjuvant treatment of colorectal hepatic ...metastases. The objective responses of 41 patients (73%) were reported ... See full document

6

Regulatory expression of MMP-8/MMP-9 and inhibition of proliferation, migration and invasion in human lung cancer A549 cells in the presence of HGF variants

Regulatory expression of MMP-8/MMP-9 and inhibition of proliferation, migration and invasion in human lung cancer A549 cells in the presence of HGF variants

... number of cells that migrated were counted in a blinded fashion based on the camera ...out. In-vitro Boyden chamber experiment Invasion assays were carried out according to our ... See full document

37

Musashi-1 promotes a cancer stem cell lineage and chemoresistance in colorectal cancer cells

Musashi-1 promotes a cancer stem cell lineage and chemoresistance in colorectal cancer cells

... intracellularly in the ...inhibiting the Rack1 or p38 signalling pathways 41 . Inhibition of the mTORC1 pathway also prevents apoptosis in cancer cells 42 ... See full document

13

Correlation Between PET/CT Parameters and KRAS Expression in Colorectal Cancer.

Correlation Between PET/CT Parameters and KRAS Expression in Colorectal Cancer.

... Wis). The MTVs were measured from attenuation-corrected FDG-PET images. The MTV was defined as the sum of metabolic volumes of the primary ...tumors. The volume boundaries ... See full document

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