天主教輔仁大學課程大綱天主教輔仁大學課程大綱

(1)

請尊重智慧財產權及著作權，不得非法影印任何有版權的著作請尊重智慧財產權及著作權，不得非法影印任何有版權的著作

Please respect the intellectual property rights and use the materials legally.

課程名稱

Course Title ^{分子生物學}

授課教師

Instructor ^唐烽堯學年度

Academic year

94 ^學期

Semester 1

課程大綱

教學目標:

本課程以傳授基礎分子生物學知識為主，目的在於使學生能夠學習到基本觀念，並在將來學習細胞生物學及基因工程學上能得以銜接。

課程範圍:

本課程範圍將以講解真核細胞的DNA 結構,transcription, RNA splicing, protein translation, 基因體學及蛋白質體學為主

授課方式:

以Powerpoint投影片動畫圖解為主，課本為輔課程進度及綱要:

1. The molecular nature of genes 2. An introduction to gene function

3. Eukaryotic RNA polymerases and their promoters 4. General transcription factors in eukaryotes 5. Transcription activators in eukaryotes

6. Chromatin structure and its effects on transcription 7. Messenger RNA processing I: splicing

8. Messenger RNA processing II: capping and polyadenylation 9. The mechanism of translation I: initiation

10. The mechanism of translation II: elongation and termination 11. Ribosomes and transfer RNA

12. DNA replication I: basic mechanism and enzymology 13. DNA replication II: detailed mechanism

14. Homologous recombination 15. Genomics and Proteomics 參考書籍:

Molecular Biology 3rd edition by Robert F. Weaver.

Publisher: McGraw Hill

評分方式: 期中考: 40%

期末考: 50%

小考: 10%