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Trends in diabetes mellitus among Taiwanese adolescents and young adults during 2000-2009: a national population-based cohort study

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P O S T E R P R E S E N T A T I O N Open Access

Trends in diabetes mellitus among

Taiwanese adolescents and young adults

during 2000-2009: a national population-based cohort study

Meng-Che Tsai

1*

, Chih-Ching Chang

2

, Yen-Yin Chou

1

, Shio-Jean Lin

1

, Sheng-Hsiang Lin

3,4

From 7th APPES Biennial Scientific Meeting

Nusa Dua, Bali. 14-17 November 2012

Aims

To describe trends in the prevalence and incidence of diagnosed diabetes mellitus (DM) among Taiwanese adolescents and young adults.

Methods

A subset of Taiwan National Health Insurance Research Database containing complete inpatient and outpatient data of one million beneficiaries randomly drawn from the national population of 23 millions was used for this retrospective longitudinal study during 2000-2009.

Patients aged 10-24 years old who had at least two out- patient visit claims and/or one inpatient hospitalization claim for diabetes based on the International Classifica- tion of Disease, 9

th

Revision, Clinical Modification (ICD- 9-CM) code 250.XX were included. Patients were further subdivided as having type 1 DM, if they had been hospitalized due to diabetic ketoacidosis (ICD-9- CM code 250.1X) and/or had received claims for ICD- 9-CM 250.X1 or 250.X3. Those who failed abovemen- tioned criteria for type 1 DM were classified as having type 2 DM. Age-specific and age-sex-adjusted standar- dized annual incidence and prevalence with 95% confi- dence interval (CI) by the calendar year 2004 were calculated to describe their trends in different gender and age groups.

Results

During the study period, the age-sex-adjusted prevalence and mean annual incidence of diagnosed type 1 DM were

521.59 per 100,000 enrollees (95% CI 514.89-528.59) and 3.24 per 100,000 enrollees (95% CI 2.71-3.77), respectively.

No remarkable sexual difference in the annual incidence of type 1 DM was noted, whereas a male/female ratio of 0.85 (95% CI 0.82-0.88) in the prevalence was observed. The annual incidence of type 1 DM decreased with age and remained stable over these 10 years; while the prevalence remained constant through adolescence and varied from year to year. Meanwhile, the adjusted prevalence and mean annual incidence of type 2 DM were 834.14/100,000 (95%

CI 825.64-842.63) and 120.19/100,000 (95% CI 116.96- 123.43), respectively. No remarkable sexual predominance in the prevalence of type 2 DM was noted, whereas a male/

female ratio of 0.86 (95% CI 0.79-0.92) was observed in the prevalence. The annual incidence of type 2 DM increased with age and decreased gradually over the recent 10 years;

while the prevalence was still on the increase in this age group.

Conclusion

The incidence and prevalence of type 2 DM came to outnumber that of type 1 DM during adolescence.

Although the incidence of newly diagnosed type 2 DM decreased, a rising trend in the prevalence of type 2 DM still existed. A public health policy may be needed to com- bat the emerging health issue of adolescent diabetes.

Authors’ details

1

Department of Pediatrics, National Cheng Kung University, College of Medicine, National Cheng Kung University, Tainan, Taiwan.

2

Department of Environmental and Occupational Health, College of Medicine, National Cheng Kung University, Tainan, Taiwan.

3

Research Center of Clinical Medicine, Cheng Kung University Hospital, College of Medicine, National

1

Department of Pediatrics, National Cheng Kung University, College of Medicine, National Cheng Kung University, Tainan, Taiwan

Full list of author information is available at the end of the article

Tsai et al. International Journal of Pediatric Endocrinology 2013, 2013(Suppl 1):P31 http://www.ijpeonline.com/content/2013/S1/P31

© 2013 Tsai et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

(2)

Cheng Kung University, Tainan, Taiwan.

4

Institute of Clinical Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan.

Published: 3 October 2013

doi:10.1186/1687-9856-2013-S1-P31

Cite this article as: Tsai et al.: Trends in diabetes mellitus among Taiwanese adolescents and young adults during 2000-2009: a national population-based cohort study. International Journal of Pediatric Endocrinology 2013 2013(Suppl 1):P31.

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Submit your manuscript at www.biomedcentral.com/submit

Tsai et al. International Journal of Pediatric Endocrinology 2013, 2013(Suppl 1):P31

http://www.ijpeonline.com/content/2013/S1/P31

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