生技醫療與智慧化醫療之產業趨勢與商機
主題:打造全人照護目標的智慧醫院
講題:智慧健康照護–由AI醫院擴展至健康生活圈 Smart Healthcare
–
Extending from AI Hospital to Healthcare Ecosystem臺北醫學大學附設醫院
院長 陳瑞杰教授
Ray-Jade Chen, MD, Msc Superintendent & Professor of Surgery Taipei Medical University Hospital Sep 18, 2019智慧健康照護–由AI醫院擴展至健康生活圈
⊙ 照護制度轉型
(Healthcare System Transformation)⊙ AI醫院
(AI Hospital)⊙ 健康生活圈
(Healthcare Ecosystem)全球人口改變與健康照護趨勢
Global Trends in Healthcare
Rapid Ageing Threatens
(2050, ↑60y) 快速老化
2 billions
(21.5%)
Higher Health Expenditure
高耗醫療
10.5 %
Global GDP (2020, OECD) Lower Fertility
低生育率
(Caregivers for age 80+)
Today 7 2030 4 2050 3
Chronic care
Healthcare Demand Increases with Age
供需失衡
>60 y
75%=1 disease 50%≥2 disease
Critical care shortfall in US
22 % (2020) 35 % (2030)
3
Affordability (可負擔)
Continuity (連續性)
Digital (數位化)
Engagement (認同感)
Four Themes
• Healthcare Expense:
72% are concerned
• Most wanted plan: IPD, ED & dental care
• Retail clinic: growing
• Primary care: dropping
• Digital Solutions: 70%
preferred, eg, digital appointment reminders
• Behaviors change to reduce cost ….
• Better incentives for
• 5000 steps/day
• weight reduction
• regular exercise
健康照護的消費觀
Healthcare Consumerism
(McKinsey CHI Survey, 2018)醫療照護產業數位轉型
Digital Transformation in Healthcare
Reactive vs. Proactive & Predictive
One Size Fits All vs. Personalized
Institution Centered vs. Decentralized
Paternalistic vs. Empowered
Volume Based vs. Value Based
5
精準醫學
Precision Medicine - P4 Medicine
P4
–預測
(Predictive)–預防
(Preventive)–參與
(Participatory)–個人
(Personalized)何謂健康?
Determinants of Health and Contribution to Premature Death
(Steven A. Schroeder, M.D, NEJM 2007)
Source: Schroeder, SA. (2007). We Can Do Better – Improving the Health of the American People.
NEJM. 357:1221-8.
From Clinic to Community:
A Holistic Approach to Health Care
7
Precision Medicine
(醫學是精準化或大眾化?)
• Medicine
– “one-size-fits-all” approach
• Precision Medicine
– takes into account “individual differences”
• genes, environments, and lifestyles
The Health Care Industry
• Complex, Comprehensive and Expensive
• Too slow to embrace the digital technology
• But recognize the data could improve outcomes
智慧健康照護–由AI醫院擴展至健康生活圈
⊙ 照護制度轉型
(Healthcare System Transformation)⊙ AI醫院
(AI Hospital)⊙ 健康生活圈
(Healthcare Ecosystem)建構智慧醫院之關鍵
To build a future-proofed facility that uniquely balances
three key aspects
– excellence in clinical outcome (卓越) – efficiency in the supply chain (效率)
– enhancement of the patient experience (有感)
11
智慧醫院
SMART-AI HOSPITAL
Health
Checkup Smart
Pharma
cy Smart
Laboratory Smart
Scheduling
Smart Station, Wards, ICUs, and OP Room Smart OPD
Smart Radiolog
y Robotic Service
Counter
Tele-care & Long-term Care Service
Smart Auxiliary Smart ER
• Hospital info (Website)
• Patient Service (App)
• Structured Orders &
Reports
• Structured EMRs
• Data & Seamless Care Workflow
• Scheduling &
Reports
• Tele-care Service
• Long-term Care Service
• CRM Management
• Logistic Supply Chain
• Smart Building
全球健康照護現況與未來發展
Global Healthcare (Economist, March 4th, 2017)
The “Healthcare Value Chain”
(健康照護價值鏈)
– care: continuous & proactive – incentives shifting:
“outcomes are the new incomes”
“Health on Demand ( 隨需而醫 )”
13
智能藥局 - 精準.即時.安全
Automation Pharmacy
自動包藥
VBM 藥師確認 適用族群
慢簽.多重
OPD 智慧藥盒
IPD (Automation Pharmacy)
Prescription
Order check
UD藥囑
QR code
Stat / Return
Confirmation
Decentralized Centralized
Automated Dispensing Cabinets (ADC)
安全分裝
清楚標示
Carousel + Tosho餐包
即時取藥(2-5mins)
Traditional (開放式)護理站 New (隱藏式)護理站
智慧病房- 護理站進化
15
護理白板
(即時動態資訊)床頭卡
(即時互動)
巡房系統
住 (出)院
IPD & Discharge
跨單位 / ISBAR系統
無出院櫃檯
(病房完成結帳
80%)
電子藥櫃 (ADC)
護理師候藥時間 0.5-2時 2-5分
使用率:日均 7次 (最高達37次)
團隊交班全院無紙化
Key Drivers in the Healthcare AI
To solve key problems :
• Reducing
workload (降低工作負荷)
– time and costs
• Reducing errors (減少人為錯誤)
– Improve service quality
• Providing virtual assistance
– to patients and providers
• Improving accuracy of diagnosis (改善診斷正確率)
– with imaging and procedures
17
No Data, No AI
The Process
DataGenerated Data
Stored Data
Processing Actionable Insights
Big Data Artificial Intelligence
行動化應用
巡房系統/交班系統
生理量測 檢驗資料(趨勢圖)
影像/超音波檢查 用藥紀錄(院內外) 會診紀錄 Note紀錄系統 ISBAR交接班
病歷結構化 照護自動化 & 行動化
Structured EMR & Mobile HIS
VS/R/NP:309台
PGY:15台
護理單位: 206台
行政單位 : 100台
普及率
100%跨單位(高危)運送交接班
19
重症照護 -臨床決策系統
Ted-ICU & Decision Support System (DSS)
• ICU 70 床
全面使用
Dashboard作業,
iPad同步上線
•自動上傳:
-生理指標:血壓、脈搏、血氧、呼吸 -檢查數值:心電圖、超音波
•顏色區分檢傷級數
Auto-Transmission 自動化拋轉
Auto-Integration 自動化整合
Auto-Calculating &
Warning
自動化計算與警示
Auto-Transformation 自動化醫療記錄整合
AI-Assisted 3-hour Sepsis Bundle Care
降低死亡率:10%
LOS: 縮短 25%
AI
核心技術 具體成果 專業團隊
智慧醫療影像
陳震宇李境嚴 醫學影像分析語意標注格式智慧睡眠醫學
劉文德李岡遠 居家物聯網對話機器人李信謙
及科技輔具 智慧復健
3D動態輔具設計輔助科技陳適卿 康峻宏 彭志維
智慧醫院
資料可視化 區塊鏈技術 癌症智慧系統 NLP深度學習 陳瑞杰
羅友聲 袁國慶 陳俊佑
智慧病理
陳志榮 病理影像分析語意標註格式智慧病患安全
李友專雪 兒碧 監督及非監督機器學習分類智慧胸腔醫學
智慧氣喘監測 智慧肺結核診斷
手機智慧回饋 結核菌智慧診斷 郭漢彬周俊良
余明治
智慧骨鬆預測
陳榮邦方嘉郎 股骨型態分析運算Actionable Insights
(北醫大人工智慧團隊,
TMU AI Retreat, 2019.06,29)21
智慧健康照護–由AI醫院擴展至健康生活圈
⊙ 照護制度轉型
(Healthcare System Transformation)⊙ AI醫院
(AI Hospital)⊙ 健康生活圈
(Healthcare Ecosystem)TMU Healthcare Ecosystem
23
健康照護系統-未來挑戰與機會
Challenges & Opportunities
ACCELERATED AGING POPULATION
RISING OF NCD BURDEN
SHORTAGE OF DOCTORS, NURSES &
CARETAKERS
ABSENT LONG-TERM CARE
INFRASTRUCTURE
“Decentralization” of healthcare system to tackle many issues afflicting developed countries
Personal Health Records (PHRs)
PHRs have the potential
– to give patients or healthy people
• fine-grained (精釀)
• personalized (個人)
• secure (安全)
– to access & control their own medical data – to enable self-management of care
A Ledger of Me: Personalizing Healthcare Using Blockchain Technology (Gary Leeming*, James Cunningham and John Ainsworth, Frontiers in Medicine | July 2019 | Volume 6 | Article 171)
25
Challenges after Digitized Healthcare
• Challenges
– enable data sharing (共享), or interoperability (共通), between data sources and systems
• Governance (治理)
– Protect the personal and private data (PHR) – need for more “Trust”
• transparency of consent (同意書透明化)
• anonymization
(匿名化)• data ownership
(資料所有權)• “No Trust, No Data”
A Ledger of Me: Personalizing Healthcare Using Blockchain Technology (Gary Leeming*, James Cunningham and John Ainsworth, Frontiers in Medicine | July 2019 | Volume 6 | Article 171)
Fundamentals of Blockchain Technology
(區塊鏈技術基礎)
1. Distributed Network (分散式網路): decentralized
P2P architecture
2. Shared Ledger (共享式帳本):
no
power to tamperor alter data
3. Digital Transactions
(數位交換)
:• encrypted and digitally signed to guarantee authenticity
and accuracy• Blocks are added in a linear, chronological order
27
No Blockchain, No Trust
- Adoption of Blockchain-based PHR
• Solutions of Challenges ?
– Smart contract-based permit
(智能合約)• Event-driven Consent (項目導向同意書)
• Self-governance (自主管理)
– Ledger-based distributed network
(帳本分散式網路)• Trust (互信): immutability (零竄改)
• Transparency (透明): no arbitration (仲裁) or authenticate (認證)
• Traceability (可追溯): drug/food logistic
• Dis-intermediation (去中介)
29
HEALTHCARE DATA SHARING
From institution-centric
via Blockchain
to patient-centric
(patient-mediated and
patient-driven)
31
BLOCKCHAIN AT TMUH
Since Nov. 2017, we have expanded the function of our blockchain-based app, iWellChain:
HIGH-END
HEALTH EXAM REPORTS
IT Pass +
NHI Health Account PATIENT SUPPORT PROGRAM
(CLINICAL TRIALS)
HEALTH ACCOUNT
& INTER- HOSPITAL REFERRALS
健保醫療資訊雲端查詢系統
-資訊共享與節制浪費
(2019.07.26 BioAsia)雲端藥歷系統(西醫用藥) (3個月)
手術紀錄
(6個月)
中醫用藥紀錄 (3個月)
復健醫療紀錄(12個月)
過敏藥物紀錄(永久)
特定藥品用藥紀錄
(特定管制藥品&特定凝血因子用藥)
(6個月)
檢查檢驗紀錄
(6個月)
牙科處置及手術
(24個月)
檢查檢驗結果
(Report & Lab Data)
(6個月)
出院病歷摘要(6個月)
Patients
分類 資料類型 資料說明 SDK釋出 醫院上傳時
效 開放查詢區間
個人資料 生理量測 ※自行輸入資料
輸入維護 自費健檢資料登錄 ※自行輸入資料
健保申報 資料
就醫資料
西醫門診資料 V
<24小時
近3年~前2日 中醫門診資料 V
牙醫門診資料 V
住院資料 V
用藥資料 同門牙住資料 手術資料 同門牙住資料
過敏資料 V 104年1月1日起
出院病歷 X 104年1月1日起
檢驗檢查結果
血糖、血脂檢驗資料 V
近3年~前2日 其他檢驗資料 V
影像或病理檢查資料 V
預防與保健
成人預防保健結果 V
於國民健康署登錄/上傳時間
癌症篩檢結果 V
預防接種資料 V 依檢送疾管署預防接種資料
器捐或安寧緩和醫療意願 V 依檢送衛福部醫事司資料
保險計費 健保卡狀況及領卡紀錄
保費計費明細 ※個人負擔部份
保險繳納 保險費繳納明細 ※雇主+個人明細
33
健康醫療資料交換與臺灣機會
Health Data Interoperability & Taiwan’s Opportunity
TAKEAWAYS
• No data, No AI
• No Trust, No Data (interoperability & sharing)
• No Blockchain, No Trust (smart contract & ledger-based distributed network)
• Big Data Data Economy
• AI Hospital Healthcare Ecosystem AI
Blockchain
35