生長因子誘發腫瘤細胞轉移與活化integrin相關機轉之探討; Growth factors induce cancer cells migration via activation of integrins

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ύ୯ᙴᛰεᏢᙴᏢଣ ! !

୷ᘵᙴᏢࣴز܌!

ᅺγᏢՏፕЎ!

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ғߏӢηᇨวဍዦಒझᙯ౽ᆶࢲϯ joufhsjo ࣬ᜢᐒᙯϐ௖૸!

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Hspxui!gbdupst!joevdf!dbodfs!dfmmt!njhsbujpo!wjb!

bdujwbujpo!pg!joufhsjot!

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ࡰᏤ௲௤Ǻ!෯ඵܷ!റγ!

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ࣴزғ!Ǻ!ᒘ࠮ذ!

ȐMMbj-U{v.Itjvȑ!

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ύ ๮ ҇ ୯ ΐ Μ Ύ ԃ Ϥ Д!

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ҞᒵȐDpoufoutȑ!

।ኧ!

ᕭቪ߄!ǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾ2!

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ಃ΋೽ҽǵԋମಒझ़ғ!CNQ.3!࿶җࢲϯ joufhsjo ቚу߻ӈဏဍዦಒझ౽୏܄!

ύЎᄔा!ǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾ4!

मЎᄔा!ǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾ5!

ᆣፕ!ǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾ6!

ჴᡍ׷਑ᆶБݤ!!ǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾ22!

่݀ᆶ૸ፕ!!ǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾ26!

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ಃΒ೽ҽǵĮvȕ3!joufhsjo!ୖᆶ!tuspnbm!dfmm.efsjwfe!gbdups.2Į 0DYDS5!ၡ৩ ᇨᏤ೬ମԺዦಒझᙯ౽!

ύЎᄔाǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾ42!

मЎᄔाǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾ43!

ᆣፕǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾ44!

่݀ᆶ૸ፕǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾ4:!

ୖԵЎ᝘ǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾǾ64!

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ᕭቪ߄!

ȐBccsfwjbujpoȑ!

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CNQ.3! Cpof!npsqiphfofujd!qspufjo.3!

FDN! Fyusbdfmmvmbs!nbusjy!

FSL! Fyusbdfmmvmbs!tjhobm!sfhvmbufe!ljobtf!

GBDT! Gmpx!dzupnfusz!bobmztjt!

GCT! Gfubm!cpwjof!tfsvn!

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IQD! Ifnbupqpjfujd!dfmmt!

JLL! JțC!Ljobtf!

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QWEG! Qpmzwjozmejgmvpsjef!

SHE! Bsh.Hmz.Btq!

SU! Sfwfstf!usbotdsjqujpo!

TEG.2Į! Tuspnbm!dfmm!efsjwfe!gbdups.2Į!

tjSOB! Tnbmm!joufsgfsjoh!SOB!

UHG.ȕ! Usbotgpsnjoh!hspxui!gbdups.ȕ!

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ಃ΋೽ҽ!!

Ptufpcmbtut.efsjwfe!CNQ.3!foibodft!uif!npujmjuz!pg!qsptubuf!dbodfs!dfmmt!

wjb!bdujwbujpo!pg!joufhsjot!

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ᄔा!

ȐBctusbduȑ!

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ᄔा!

!!!!߻ӈဏဍዦಒझᙯ౽Կମᓐࢂ࣬྽தـޑӝٳੱǶମᓐ׎ԋೈқ.3ȐCpof!

npsqiphfofujd!qspufjo.3, CNQ.3ȑ୷ҁ΢ࢂҗԋମಒझȐPtufpcmbtuȑϩݜЪתᄽ

๱΋ঁମᓐԋ׎ޑख़ाفՅǶJoufhsjo ӧথ٢ᜪಒझ΢ࢂЬाޑᗹ๱ӢηǴ٠Ъᆶ ٢ ᕎ ಒ झ ᙯ ౽ ډ ମ ᓐ Ԗ ஏ Ϫ ϐ ᜢ ߯ Ƕ ך ॺ ว ౜ ԋ ମ ಒ झ ୻ Ꭶన Ȑ Ptufpcmbtu!

Dpoejujpo!Nfejvn-!PCDNȑ྽ύޑ CNQ.3 ቚуΑΓᜪ߻ӈဏဍዦޑᙯ౽аϷဍዦಒ झ߄य़΢ ȕ˄ Ϸ ȕ3 joufhsjo!߄౜Ƕ๏ϒ ȕ˄ Ϸ ȕ3 joufhsjo!ޑൂਲ਼לᡏ܈ tnbmm!

joufsgfsjoh!SOBȐtjSOBȑૈ୼׭ڋҗ CNQ.3 ቚу߻ӈဏဍዦಒझޑᙯ౽Ƕךॺ๏

ϒ߻ӈဏဍዦಒझ Qiptqibujezmjoptjupm!4.ljobtfȐQJ4Lȑ׭ڋᏊ)MZ3:5113*-!

Fyusbdfmmvmbs! tjhobm! sfhvmbufe! ljobtf Ȑ FSL ȑ ׭ ڋ Ꮚ )QE:916:*-! Ovdmfbs!

gbdups.lbqqbC

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OG.țC

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׭ڋᏊ)QEUD*܈ JțC ೈқ䁙׭ڋᏊ)UQDL*!೿ૈ׭ڋҗ CNQ.3 ᇨᏤޑဍዦಒझᙯ౽аϷ joufhsjo!߄౜Ƕ!ԜѦǴஒಒझ๏ϒ CNQ.3 ᇨᏤΑ Blu-! FSL-! JțC! ljobtf! Į0ȕ! )JLLĮ0ȕ*-! JțCĮ ک ! q76Tfs⁶⁴⁷! ᕗ ለ ϯ Ǵ а Ϸ!

țC.mvdjgfsbtf!ࢲ܄Ƕҗ PCDN!྽ύ़ғԶٰޑ!CNQ.3!܌ቚу JLLĮ0ȕ ک!q76Tfs⁶⁴⁷ ᕗለϯϷ țC.mvdjgfsbtf!ࢲ܄ڙ MZ3:5113!ک!QE:916:!ٰ׭ڋǶ!ќѦǴ!CNQ.3!

tjSOB!෧ϿΑҗ PCDN ᇨᏤޑಒझᙯ౽аϷ joufhsjo ߄౜ቚуǶ!CNQ.3!tjSOB!Ψё

׭ڋΑҗ PCDN!ᇨᏤቚуޑ FSL-!Blu!ک!OG.țC ࢲ܄Ƕ೭٤่݀ࡌ᝼ ptufpcmbtu ़ ғԶٰޑ CNQ.3!ᙖҗ೸ၸ Blu ک FSLǴԶ٩ׇࢲϯΑ JLLĮ/ȕ!ک!OG.țCǴ೷ԋΑ ȕ2!

ک!ȕ4!joufhsjot ߄౜ቚу٠ЪගٮΑ߻ӈဏဍዦಒझޑᙯ౽Ƕ!

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Bctusbdu!

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cpof! npsqiphfofujd! qspufjo.3! )CNQ.3*! jt! dpotujuvujwfmz! tfdsfufe! cz!

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ps!ȕ4!joufhsjo!joijcjufe!uif!CNQ.3.joevdfe!jodsfbtf!pg!uif!njhsbujpo!pg!

qsptubuf!dbodfs!dfmmt/!Usfbunfou!pg!QD.4!dfmmt!xjui!QJ4L!joijcjups!)MZ3:5113*-!

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beejujpo-!usfbunfou!pg!QD.4!dfmmt!xjui!CNQ.3!joevdfe!Blu-!FSL-!JțC!ljobtf!

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Uif! PCDN.efsjwfe! CNQ.3.nfejbufe! jodsfbtf! pg! JLLĮ0ȕ-! q76! Tfs⁶⁴⁷! qiptqipszmbujpo-!boe!țC.mvdjgfsbtf!bdujwjuz!xbt!joijcjufe!cz!MZ3:5113!boe!

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vqsfhvmbujpo!pg!joufhsjot/!CNQ.3!tjSOB!bmtp!tvqqsfttfe!uif!PCDN.joevdfe!FSL-!

Blu!boe!OG.țC!bdujwbujpo/ Ublfo!uphfuifs-!uiftf!sftvmut!tvhhftu!uibu!uif!

ptufpcmbtu.efsjwfe!CNQ.3!bdut!uispvhi!Blu!boe!FSL-!xijdi!jo!uvso!bdujwbuft!

JLL!Į/ȕ!boe!OG.țC-!sftvmujoh!jo!uif!bdujwbujpo!pg!ȕ2!boe!ȕ4!joufhsjot!boe!

dpousjcvujoh!up!uif!njhsbujpo!pg!qsptubuf!dbodfs!dfmmt/

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ᆣፕ!

ȐJouspevdujpoȑ!

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ମᓐࢂ΋ঁ࣬྽தـဍዦᙯ౽ޑՏ࿼Ƕ೚ӭဍዦ੝ձୃངᙯ౽ԿମᓐǴхࡴ٢ ᕎǵ߻ӈဏᕎکޤᕎȐNvoez-!3113ȑǶӧऍ୯؂ԃԖѤԭ࿤ΓԝΫǴ߈ЯѤϩϐ΋

ޑΓԝܭᕎੱ٠Ԗ 81ʘࢂᑡ஻Ԗ٢ᕎǵޤᕎ܈߻ӈဏᕎȐNvoez-!3113ȑǶ่݀Ǵӧ ऍ୯؂ԃԖεܭ 461-111 Γԝܭମᓐᙯ౽ȐNvoez-!3113ȑǶᕎੱᙯ౽Ǵࢂ೷ԋᕎੱ

ੰΓԝΫޑЬӢǴࢂ΋ঁፄᚇΞӭ໘ࢤޑၸำȐWbo(u!Wffs!boe!Xfjhfmu-!3114ȑǶ ڂࠠӦǴᕎੱᙯ౽ޑวғх֖Αኧঁ؁ᡯǺхࡴಒझᙯࠠȐusbotgpsnbujpoȑکဍ ዦғߏǴՈᆅཥғȐbohjphfoftjtȑکరЃᆅ׎ԋȐmznqibohjphfoftjtȑǴᙖҗϣ ᅖБԄȐjousbwbtbujpoȑဍዦಒझ຾ΕՈࢬൻᕉύǴଶݲȐbodipsbhfȑکߕ๱

Ȑbuubdinfouȑӧ኱ޑᏔ۔΢Ǵӆ೸ၸѦᅖБԄȐfyusbwbtbujpoȑ੆ዎډ኱ޑᏔ۔

ϣǴ٠Ъکჴ፦Ꮤ۔΋ଆቚғȐIbobibo!boe!Xfjocfsh-!3111ȑȐGjh/!2ȑǶဍዦಒ झޑᙯ౽ૈΚࢂख़ाܭ೭٤؁ᡯ٠ЪӢԜᜢ߯๱ᕎੱᙯ౽Ƕ!

!!!!Joufhsjotࢂ΋ဂऀ೸ጢڀᗹ๱܄ޑௗڙᏔх֖ΑԖ2:ঁĠک9ঁġԛൂՏ܌ಔ ԋǴԶаߚӅሽӦ࣬ϕբҔБԄѐ׎ԋ35ᅿόӕޑ!ifufspejnfsjdௗڙᏔȐGjh/!

3ȑǶӧಒझጢ΢όӕjoufhsjo!tvcvojutಔӝϢ೚ಒझѐᒣᇡکϸᔈډኧᅿόӕ fyusbdfmmvmbs!nbusjy!qspufjoȐFDNȑǴхࡴgjcspofdujo-!mbnjojo-!dpmmbhfo!ک!

wjuspofdujo!ȐIvnqisjft-!2000ȑǶӢࣁjoufhsjotࢂЬाܭಒझᗹߕډFDNޑௗڙ ᏔϩηǴѬॺתᄽ๱ಒझᚈӛૻ৲໺ሀޑख़ा໺ૻᏔǴፓ࿯ಒझӸࢲȐtvswjwbmȑǵ ϩϯȐejggfsfoujbujpoȑǵቚғȐqspmjgfsbujpoȑǵᙯ౽ȐnjhsbujpoȑǴکಔᙃ ख़ཥ༟೷Ȑujttvf!sfnpefmjohȑȐHjbodpuuj!boe!Svptmbiuj- 1999ȑǶJoufhsjo ᆶဍዦғߏԖᜢȐCspplt!fu!bm/-!2::5ǹCspplt!fu!bm/-!2::6ȑǴک่ဉᕎک໵

Յનዦ஻ޣޑӸࢲԖᜢȐBmcfmeb!fu!bm/-!2::1ǹIjflfo!fu!bm/-!2::7ȑǴ٠ᆶ٢ ᕎಒझᙯ౽ډମᓐԖᜢȐQfdifvs!fu!bm/-!3113ȑǶԜѦǴĮvȕ3 joufhsjo!ᆶ߻ӈ ဏဍዦғߏǴ!bohjphfoftjtǵ!tvswjwbm!ک!jowbtjpo!ԖᜢȐDppqfs!fu!bm/-!3113ǹ Lvnbs!fu!bm/-!3114ȑǶӧಒझޑჴᡍȐJo!wjuspȑύǴว౜joufhsjot೸ၸ೚ӭFDN!

tvctusbuftᔅշ߻ӈဏဍዦಒझ!beiftjpo!ک!njhsbujpoȐDppqfs!fu!bm/-!3113ȑǴ ٠Ъऀၸϣጢ౽ՉȐusbotfoepuifmjbm!njhsbujpoȑȐXboh!fu!bm/-!3116ȑǶ!

!!!!Cpof!npsqiphfofujd!qspufjotȐCNQtȑԖຬၸ31ᅿԋ঩Ǵࢂឦܭusbotgpsnjoh!

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6

hspxui!gbdups-ȕΰUHG-ȕαຬભৎ௼Ǵ٠Ъӧ୏ނჴᡍȐJo!wjwpȑ΢ǴᙖҗѬॺᐱ

੝ޑૈΚѐᇨᏤ౦தޑ೬ମϷମᓐ׎ԋȐSfeej!fu!bm/-!2::5ǹVsjtu!fu!bm/-!2:76ȑ ȐGjh/!4ȑǶӵӕځдUHG-ȕຬભৎ௼Ǵ!CNQtૻဦᙖҗऀጢޑtfsjof0uisfpojof!

ljobtft!ᆀࣁ!uzqf!JB-!JC!ک!uzqf!JJ!ௗڙᏔٰፓ௓!ȐNjzb{bxb!fu!bm/-!3113ȑǶ CNQೈқፓ࿯ምᛖම೏ൔᏤܭ೚ӭࠠᄊޑᕎੱϐύǶCNQt!೏ว౜תᄽ΋ঁख़ाޑف Յӧဍዦಒझޑᙯ౽ǴႽࢂޤᕎǵطᕎک໵ՅનዦȐMbohfogfme!fu!bm/-!3114ǹItv!

fu!bm/-!3116ǹSpuiibnnfs!fu!bm/-!3116!ȑǶCNQ.5-.7-ک.8߄౜ӧ߻ӈဏဏᕎᆶ ମᓐᙯ౽ϐύȐIbnez!fu!bm/-!2::8ΙNbtveb!fu!bm/-!3114ȑǶCNQ.3!ම೏ࡰрᜢ

߯๱٢ᕎဍዦಒझਲ਼ޑᙯ౽Ƕ!

ମᓐ़ғғߏӢηȐCpof.efsjwfe!hspxui!gbdupsȑکᖿϯનȐdifnpljoftȑ Ψתᄽ๱ӵᔼᎦӢηޑύЈفՅ֎Ї๱٢ᕎǴ߻ӈဏဍዦಒझᙯ౽Կମᓐಔᙃ ȐNvoez-!3113ȑǶԋମಒझ़ғӢηȐPtufpcmbtu.efsjwfe!gbdupstȑ୷ҁ΢җΓ ᜪ ԋ ମ ಒ झ Ȑ ptufpcmbtut ȑ ϩ ݜ ᡉ Ң ת ᄽ ๱ ΋ ঁ ᜢ ᗖ ف Յ ֎ Ї Ո ౚ ྍ ಒ झ Ȑifnbupqpjfujd!dfmmtȑډମᡎȐNbesje!fu!bm/-!3112ǹNvoez-!3113ȑǶฅԶǴ Ptufpcmbtu.efsjwfe!gbdupst!ჹܭΓᜪ߻ӈဏဍዦಒझ΢joufhsjo߄౜ک౽Չࢲ

୏Κૈ୼Їวޑ่݀ϝԖ೚ӭ҂ޕϐೀȐGjh/!5ȑǶךॺଷ೛ptufpcmbtu.efsjwfe!

CNQ.3ૈ୼ፓ࿯joufhsjo߄౜کߦ຾߻ӈဏဍዦಒझᙯ౽Ƕךॺว౜ptufpcmbtu!

dpoejujpofe!nfejvn!)PCDN*ቚуΓᜪ߻ӈဏဍዦಒझ౽Չکಒझ΢joufhsjo߄౜Ƕ CNQ.3! tjSOB ஑ ΋ ܄ Ӧ ෧ Ͽ җ PCDN! ᇨ Ꮴ ޑ ߻ ӈ ဏ ဍ ዦ ಒ झ ౽ Չ ک ဍ ዦ ಒ झ ΢ joufhsjo ߄ ౜ Ƕ Ԝ Ѧ Ǵ Blu-! FSL-! JLLĮ/ȕʳ ک ! OG-țC! ૻ ৲ ၡ ৩ ё ૈ ୖ ᆶ ӧ җ ptufpcmbtu!efsjwfe!CNQ.3!ቚуjoufhsjo߄౜کဍዦಒझ౽Չ྽ύǶ!

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ߕკ΋!!UUif!tufqt!jowpmwfe!jo!uvnpvs.dfmm!nfubtubtjt!gspn!b!qsjnbsz!tjuf!

up!uif!tlfmfupo/!

Fbdi!pg!uiftf!tufqt!sfqsftfout!b!qpufoujbm!uifsbqfvujd!ubshfu!up!sfwfstf!

ps!qsfwfou!nfubtubujd!cpof!ejtfbtf/!Uif!qsjnbsz!nbmjhobou!ofpqmbtn!qspnpuft!

ofx!cmppe.wfttfm!gpsnbujpo-!boe!uiftf!cmppe!wfttfmt!dbssz!uif!dbodfs!dfmmt!

up!dbqjmmbsz!cfet!jo!cpof/!Bhhsfhbuft!pg!uvnpvs!dfmmt!boe!puifs!cmppe!dfmmt!

fwfouvbmmz!gpsn!fncpmjtnt!uibu!bssftu!jo!ejtubou!dbqjmmbsjft!jo!cpof/!Uiftf!

dbodfs!dfmmt!dbo!uifo!beifsf!up!uif!wbtdvmbs!foepuifmjbm!dfmmt!up!ftdbqf!

uif!cmppe!wfttfmt/!Bt!uifz!foufs!uif!cpof-!uifz!bsf!fyqptfe!up!gbdupst!pg!

uif!njdspfowjsponfou!uibu!tvqqpsu!hspxui!pg!nfubtubtft/!ȐBebqufe!gspn!

Nvoez-!3113ȑ!

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ߕკΒ!!Uif!Joufhsjo!Sfdfqups!Gbnjmz/!

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(14)

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(15)

10

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(16)

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ჴᡍ׷਑ᆶБݤ!

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(17)

11

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ಒझ୻ᎦȐDfmm!dvmuvsfȑǺ!

!!!!Γᜪ߻ӈဏဍዦಒझਲ਼ȐQD4-!EV256-!MoDbQ*کΓᜪମԺዦဍዦಒझਲ਼)NH.74*

ᖼԾ Bnfsjdbo!Uzqf!Dvmuvsf!DpmmfdujpoǶಒझҔ֖ 21ʘ!Gfubm!cpwjof!tfsvn ȐGCTȑǵ2ʘ!qfojdjmmjo!0tusfqupnzdjo!ϐ!SQNJ.2751 ୻ᎦǴΓᜪ೬ମԺዦဍዦ ಒझਲ਼ȐKK123ȑҗ Es/!Tfbo!Q/!Tdvmmz!)Vojwfstjuz!pg!Njbnj!Tdippm!pg!Nfejdjof-!

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ΓᜪମԺዦಒझਲ਼ȐNH.74ȑӧ୻ᎦҝғߏၲऊΖϩᅈࡕǴඤԋό֖!GCT!ޑ SQNJǶ׳ඤ୻ᎦనࡕǴdpoejujpofe!nfejvnȐDNȑሡӆ୻ᎦٿϺฅࡕԏ໣ଆٰǴӸ

(18)

ܫӧ.81±D!ӇጃǶ!

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ಒझ౽ՉჴᡍȐNjhsbujpo!bttbzȑǺ!

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MZ3:5113-!QE:916:-!QEUD!܈!UQDLǶ߈Я!3!Ø!21^5!ಒझໆӧ!311ȝm!tfsvn.gsff!

SQNJ.2751!ޑ୻Ꭶన࿼ܭ!usbotxfmm!ޑ΢ቫǴҔ!411ȝm!PCDN!࿼ܭΠቫǶܫډ!

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཮౽ՉډᘠጢޑΠቫຠߕǴёӧᡉ༾᜔ۭΠीኧಒझኧໆǶӧ؂ঁჴᡍ଺Οख़ፄǴ

؂ঁჴᡍӧΟঁόӕਔ໔ᗺӆ଺΋ԛǶ؂ঁჴᡍύǴ౽ՉޑಒझኧໆᙖҗಒझӸࢲ ჴᡍȐdfmm!wjbcjmjuz!bttbzȑ่݀ѐፓ᏾ǴҗPCDN܌Їଆޑಒझቚғਏᔈѐਠ҅Ƕ Ȑ҅ዴޑಒझ౽Չኧໆɨीኧಒझ౽Չޑኧໆ0ಒझӸࢲԭϩКȑȐDiv!fu!bm/-!

3118ǹIvboh!fu!bm/-!3118ȑǶ!

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ࢬԄಒझמೌϩ݋ȐGmpx!Dzupnfusjd!BobmztjtȑǺ!

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(19)

13

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Ҕ!3ঁ!pmjhpovdmfpujef!qsjnfs!բ44ঁ!dzdmft!ܫεǺ!

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!boujtfotf!DUBUHUHDUHHDUUUHHUHB!!

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؂ঁ!QDS!dzdmf!ӧ!:5ʚ!41ࣾǹ!66ʚ!41ࣾǹ79ʚ!2ϩដచҹΠֹԋǶ!QDS!ౢނ ӧ!3ʘ!bhbsptfӝٳ٬Ҕfuijejvn!cspnjefϣࢉޑEOB!hfmύϩ݋ȐXfo!fu!bm/-!

3117ȑǶ!

(20)

!

Usbotgfdujpo!boe!sfqpsufs!hfof!bttbz!Ǻ!

!!!!!Γ ᜪ ޑ ဍ ዦ ಒ झ Ҕ 1/9ȝh! țC.mvdjgfsbtf! qmbtnje! ک ! 1/5ȝh!

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؂ঁ xfmm ྽ύǴ٠ЪஒಒझڊΠٰǶฅࡕҔ 24-111!sqn!Ǵ!3!njo!ᚆЈࡕԏ໣ଆ ಒझ΢మనǶ؂ 31ȝm ޑಒझ΢మన֖Ԗ฻ໆȐ31.41ȝmȑޑೈқǴஒځ࿼ܭό೸Ӏ ޑ :7 ϾዬϣǶע฻ᡏᑈޑᑻӀڙ፦Ȑmvdjgfsbtf!tvctusbufȑуډ܌ԖޑኬࠔύǴ ԶհӀ೸ၸ mvnjopnfufs ೏ୀෳрٰǶ!

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кǶȐDijv!fu!bm/-!3118ȑǶ!

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಍ीϩ݋ȐTubujtujdtȑǺ!

!!!!܌ԖჴᡍኧᏵࣣаѳ֡ॶr኱ྗৡȐnfbot!²!T/F/N/ȑǶᙖҗ!Tuvefouȷt!u!uftu!

ٰຑ՗ჴᡍಔϷ௓ڋಔ໔ख़ाޑৡ౦Ƕq ॶा=1/16!ωڀԖᡉ๱ཀကǶ!

!

(21)

!

่݀ᆶ૸ፕ!

ȐSftvmut!boe!Ejtdvttjpoȑ!

!

(22)

!

่݀!

CNQ.3 ࢂ PCDN ύЬाЇว߻ӈဏဍዦಒझᙯ౽ޑӢη!

!!!!Cpof.efsjwfe!hspxui!gbdups ک difnpljoft תᄽ๱ᔼᎦӢηޑύЈفՅǴ֎

Ї๱٢ᕎǴ߻ӈဏဍዦಒझ౽ՉډମᓐȐNvoez-!3113ȑǶPCDN ჹܭ߻ӈဏဍዦಒ झ౽Չа Usbotxfmm!bttbz ຾Չϩ݋Ǵ٠Ъа PCDN ᇨᏤဍዦಒझቚғ౗ٰբࣁঅ҅

ȐDiv!fu!bm/- 2007ȑǶPCDN ٩ᐚࡋቚу boesphfo!joefqfoefou!ޑ߻ӈဏဍዦಒझ ȐQD4-!EV256ȑ౽Չ)Gjh/!6B*ΖPCDN Ψޔௗቹៜ boesphfo.efqfoefou!ޑ߻ӈဏဍ ዦಒझ౽ՉȐMoDbqȑ)Gjh/!6C*Ƕϐ߻ൔ֋ࡰр Ptufpcmbtut ёаӝԋϷϩݜ CNQ.3Ǵ Ѭתᄽ๱ӧମᓐ׎ԋکମಒझϩϯ΢ޑख़ाفՅȐVsjtu!fu!bm/-!2:76ǹ!Sfeej!fu!

bm/-!2::5ȑǶ!೭္ךॺ჋၂ࣴز PCDN ቹៜ߻ӈဏဍዦಒझ຾Չ౽ՉޑচӢǴךॺ ஒ dpouspm!ک CNQ.3!tjSOB ଌΕ Ptufpcmbtut ϐύǴฅࡕԏ໣ PCDNǶӧ Gjh/6D ύǴ!

CNQ.3!tjSOB!஑΋܄Ӧ෧ϿΑ CNQ.3!nSOB!Ϸ!qspufjo!mfwfm ޑ߄౜ǶԜѦǴCNQ.3!

tjSOB!ߔᘐҗ PCDN ᇨᏤޑ߻ӈဏဍዦಒझᙯ౽)Gjh/!6E*Ƕஒಒझ๏ϒ CNQ.3 Ψᒿ ᐚࡋቚуΑಒझޑ౽Չ)Gjh/!6F*Ƕ೭٤่݀ᡉҢ Ptufpcmbtut!ϩݜޑ CNQ.3 ӧΓ ᜪ߻ӈဏဍዦಒझ౽Չ΢תᄽ๱ख़ाޑفՅǶ!

!

Ptufpcmbtut.efsjwfe!CNQ.3 ቚу joufhsjo ߄౜ᆶ߻ӈဏဍዦಒझޑ౽ՉԖᜢ!

!!!!Ӄ ߻ ޑ ࣴ ز ම ᡉ Ң Γ ᜪ ဍ ዦ ಒ झ ΢ ȕ1 ک ȕ3 joufhsjo! Ԗ ܴ ᡉ ߄ ౜ ȐIvnqisjft!fu!bm/-!3111ǹIvboh!fu!bm/-!3118ȑǶӢԜǴךॺଷ೛ joufhsjo ё

ૈୖᆶӧ PCDN ቹៜ߻ӈဏဍዦಒझޑ౽Չ΢ǶࢬԄಒझמೌϩ݋ᡉҢ PCDN ᇨᏤΑ ಒझ߄य़΢ ȕ1 ک ȕ3 joufhsjo!߄౜)Gjh/7B*ǶҔ bouj.ȕ1 ک ȕ3 ൂਲ਼לᡏ)nBc*!)21!

ȝh0nm*ೀ౛ಒझ 41 ϩដ!܈!usbotgfdufe!ȕ1 ک ȕ3!joufhsjo!tjSOB!35 λਔܴᡉ Ӧ׭ڋҗ PCDN!ᇨᏤޑဍዦᙯ౽ȐGjh/7C'DȑǶ!CNQ.3!tjSOB!Ψ࡮לΑҗ PCDN ᇨ Ꮴ QD.4 ಒझ߄य़΢!ȕ1 ک ȕ3 joufhsjo!߄౜ȐGjh/!7EȑǶԜѦǴൂᐱ๏ϒಒझ CNQ.3!

)4.41!oh*Ψёቚу ȕ1 ک ȕ3 joufhsjo ߄౜ȐGjh/!7FȑǶ೭٤่݀ࡌ᝼ Ptufpcmbtut!

़ғٰޑ!CNQ.3!࿶җࢲϯ ȕ1 ک ȕ3 joufhsjo!sfdfqups ٰᇨᏤ߻ӈဏဍዦᙯ౽Ƕ!

!

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16

FSL203!ک!Blu!tjhobmjoh!qbuixbztୖᆶӧPCDN.efsjwfe!CNQ.3ቚуjoufhsjo!߄

౜ک߻ӈဏဍዦಒझޑ౽Չ!

!!!!Njuphfo.bdujwbufe! qspufjo! ljobtft ᆶ ᕎ ੱ ຾ ৖ Ԗ ᜢ Ȑ Tfcpmu.Mfpqpme/-!

3115ȑǶ๏ϒPCDNӧQD4ಒझ΢ࢲϯΑ!FSL203!qbuixbzǴёҗᕗለϯޑ!q53!ک!q55!

)q.FSL203*!வಃ26ϩដ໒ۈډಃ231ϩដၲډӾঢ়ٰຓܴȐGjh/!8BȑǶPCDNᇨᏤQD4 ಒझ౽Չکಒझ߄य़΢ȕ1 ک ȕ3 joufhsjo߄౜Ǵ཮ڙډFSL!joijcjups-!QE:916:!

)21!ȝN*!׭ڋȐGjh/!8CȑǶԜѦǴஒಒझଌΕFSL3!nvubouΨ׭ڋҗPCDNᇨᏤ߻ӈ ဏဍዦಒझ౽Չکȕ1 ک ȕ3 joufhsjo߄౜ȐGjh/!8C'DȑǶCNQ.3!tjSOB!Ψ෧ϿΑҗ PCDNቚуޑFSLᕗለϯȐGjh/!8EȑǶ!

!!!!BluޑࢲϯΨම೏ൔᏤᆶΓᜪဍዦಒझޑ౽ՉԖᜢȐMjv!fu!bm/-!3117ǹBnjsj!fu!

bm/-!3118ȑǶךॺճҔXftufso!cmpuujoh!bobmztjt!ࣴز!Blu!qbuixbz!ࢂցୖᆶӧ PCDNᇨᏤޑဍዦಒझ౽ՉύǶஒPCDN๏ϒQD4ቚуΑᕗለϯޑ!BluȐGjh/!9BȑǶฅԶǴ ಒझ٣ӃаQJ4L!joijcjups-!MZ3:5113!)21ȝN*!ೀ౛ܴᡉӦ׭ڋΑPCDN!ቚуಒझ ޑ౽ՉૈΚکjoufhsjo߄౜ǹBlu!nvubou!Ψ׭ڋΑPCDN!ቚуಒझ౽ՉϷjoufhsjot ߄౜ȐGjh/9C!'!9DȑǶԜѦǴCNQ.3!tjSOB!෧ϿΑPCDNቚуBluᕗለϯȐGjh/!9EȑǶ ϐ߻ࣴزࡰрǴOGˀțCޑࢲϯᆶΓᜪဍዦಒझ౽ՉکߟΕԖᜢȐCpvlfsdif!fu!bm/-!!

3118ȑǶGjh/:B!ᡉҢಒझ٣Ӄೀ౛!OG.țC!joijcjups-!QEUD!)21!ȝN*׭ڋΑPCDNᇨ Ꮴޑ߻ӈဏဍዦಒझޑ౽ՉǶԜѦǴQD4ಒझа!JțC!qspufbtf!joijcjups-!UQDL)4ȝN*!

٣Ӄೀ౛ǴΨ׭ڋΑҗPCDNᇨᏤޑဍዦಒझ౽ՉȐGjh/!:BȑǶԜѦǴ๏ϒಒझQEUD

܈UQDLΨ࡮לΑPCDNᇨᏤȕ2!ک!ȕ4!joufhsjot!߄౜ȐGjh/!:CȑǶ೭٤่݀ࡰрOG.țC ࢲϯୖᆶPCDNᇨᏤဍዦಒझ౽Չکȕ2!ک!ȕ4!joufhsjot!߄౜Ƕ!

!!!!!ךॺௗΠٰࣴزPCDNᇨᏤOGˀțCޑࢲϯޑ΢ෞӢηǶ٩ਔ໔ᗺ๏ϒPCDNڈᐟಒ झᇨᏤΑJLLĮ/ȕᕗለϯȐGjh/!:DȑǶԜѦǴஒJLLĮ܈JLLȕʳnvubouଌΕಒझܴᡉӦ׭

ڋҗPCDNᇨᏤޑဍዦಒझ౽ՉȐGjh/!:EȑǶ೭٤่݀ࡌ᝼JLLĮ/ȕࢲϯࢂୖᆶӧPCDN ᇨᏤΓᜪ߻ӈဏဍዦಒझ౽ՉǶ٩ਔ໔ᗺஒPCDN๏ϒ߻ӈဏဍዦಒझΨ೷ԋ!JțCĮʳ ᕗለϯکफ़ှȐefhsbebujpoȑȐGjh/!:DȑǶӃ߻ޑࣴزᡉҢq76!Tfs⁶⁴⁷ᕗለϯቚуOG.țC ᙯᒵࢲϯૈΚȐNbesje!fu!bm/-!3112ǹWjbupvs!fu!bm/-!3116!ȑ٠Ъq76!Tfs⁶⁴⁷ ᕗለϯ஑΋܄ޑלᡏΨҔٰᡍ᛾q76ޑᕗለϯǶ٩ྣኧঁ໔႖ޑਔ໔ᗺǴஒQD4ಒझ

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๏ϒPCDN!೷ԋΑq76!Tfs⁶⁴⁷ᕗለϯȐGjh/!:DȑǶஒಒझଌΕCNQ.3!tjSOBߔᘐΑҗPCDN ᇨᏤޑJLLĮ/ȕ, JțCĮکq76ᕗለϯȐGjh/!:FȑǶ!

!

FSL!ک!Blu!tjhobm!usbotevdujpo!ፓ௓җPCDNᇨᏤޑJLLĮ/ȕ-!JțCĮ-!q76!Tfs⁶⁴⁷ᕗ ለϯϷ!țC!mvdjgfsbtf!ࢲ܄!

!!!!ௗΠٰࣴزࢂցPCDNᇨᏤޑJLLĮ/ȕ, JțCĮکq76ᕗለϯکOG.țCࢲ܄ࢂ࿶җΑ FSL!ک!Blu!ၡ৩Ǵஒಒझ٣Ӄ๏ϒ!MZ3:5113!)21!ȝN*!܈!QE:916:!)21!ȝN*!41ϩ ដǴ׭ڋΑҗPCDNᇨᏤቚу!JLLĮ/ȕ-!JțCĮʳ ک!q76!ᕗለϯȐGjh/!21BȑΖԜѦǴ๏

ϒ!QE:916:-!MZ3:5113-!QEUD!ک!UQDL!Ψё׭ڋҗ!PCDN!ᇨᏤ!țC!mvdjgfsbtf!ࢲ

܄ȐGjh/!21CȑǶDp.usbotgfdujpo!FSL-!Blu-!JLLĮ!ک!JLLȕ!nvubou!Ψૈ୼׭ڋ җPCDNᇨᏤޑ!țC!mvdjgfsbtf!ࢲ܄ȐGjh/!21DȑǶᕴࡴԶقǴ೭٤่݀ࡌ᝼ࢲϯ!Blu!

ک!FSL!ୖᆶӧ!PCDN.efsjwfe!CNQ.3!܌ቚу!JLLĮ/ȕʿʳ JțCĮ,!q76!Tfs⁶⁴⁷ᕗለϯаϷ OG.țCޑࢲϯϐύǶ!

!

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18

૸ፕ!

!!!!߻ӈဏဍዦಒझڀԖЇΓݙҞޑ໼ӛǴ൩ࢂ৒ܰᙯ౽ډମᓐȐHsffomff!fu!

bm/-3112ǹNvoez-!3113ȑǶϩ݋ፓ௓߻ӈဏဍዦಒझᙯ౽ډମᓐޑૻဦǴࢂख़ाܭ

ૈ୼᠘ۓрלᙯ౽ݯᕍޑཥ኱ႢӢηǶךॺଷ೛ptufpcmbtu.efsjwfe!gbdupstૈޔ

ௗߦ຾߻ӈဏဍዦಒझᙯ౽Ƕךॺว౜җ!ptufpcmbtu!Զٰޑ!ptufpcmbtu.efsjwfe!

gbdupstᇨᏤΑΓᜪ߻ӈဏဍዦಒझᙯ౽Ƕ!CNQ.3 ࢂPCDNύߦ຾ಒझ౽Չکගϲ joufhsjot!߄౜ޑЬाӢηǶ!PCDN!೷ԋᙯ౽ޑځύᐒڋǴࢂᙯᒵගϲΑ!ȕ2!ک!ȕ4!

joufhsjot!߄౜٠Ъࢲϯ!Blu-!FSL-!JLLĮ/ȕ!ک!OG.țC!ၡ৩ǶCNQ.3!tjSOB!Ψ෧Ͽ ΑBlu-!FSL!ک!OG.țC!ࢲ܄Ǵ߄ҢୖᆶPtufpcmbtuቹៜ߻ӈဏဍዦᙯ౽ၸำޑύЈ فՅǶ!

!!!!߻ӈဏဍዦӧӃ຾୯ৎύЪԖቶݱӭᡂޑᖏ׉ੰำǶε೽ϩਢٯූӸޑ߻ӈဏ

ࢂڙज़ޑЪᎃ߈ޑ೬ಔᙃΨόᏤठ্ೀǶฅԶǴ߈ЯԖΖϩϐ΋ਢٯදၹԖᙯ౽௃

׎ǴڂࠠӦࢂᙯ౽ډମᓐȐNvoez-!3113ȑǶ߻ӈဏဍዦғߏکӸࢲࢂ٩ᒘ๱

boesphfojd!ipsnpoftǶቶݱᙯ౽ޑਢٯΨӢԜ٬ҔລᅟᆾগღᕍݤȐboesphfo!

efqsjwbujpo!uifsbqzȑǶ೭္ךॺว౜!PCDN!ک!CNQ.3!ߦ຾!boesphfo.efqfoefou!

)MoDbQ*ک!joefqfoefou!)QD4-!EV256*ޑ߻ӈဏဍዦಒझޑᙯ౽ǶӢԜǴ࣬ӕޑ tjhobmjoh!qbuixbzୖᆶӧPtufpcmbtutᇨᏤ߻ӈဏဍዦಒझ౽Չکගϲjoufhsjo߄

౜ύǶ!

Joufhsjotӧಒझᙯ౽کᗹߕ΢੝ձתᄽΑኰືޑفՅǶJoufhsjotҗٿঁऀጢ ԛൂՏಔԋǹ΋ঁĮک΋ঁȕԛൂՏǶӧথ٢୏ނǴ2:ঁĮک9ঁȕԛൂՏೱ่ԋӭᅿ ಔӝᡏǴѐ׎ԋ35ᅿjoufhsjotǴёа่ӝډόӕᅿᜪFDNޑբҔଛᡏ΢ȐIzoft-!

3113ȑǶӃ߻ޑࣴزᡉҢӧኧᅿဍዦಒझ΢Ǵjoufhsjotፓ௓Αಒझޑᙯ౽ϷߟΕ ȐBmcfmeb!fu!bm/-!2::1ǹIjflfo!fu!bm/-!2::7ȑǶฅԶǴӧΓᜪޑ߻ӈဏဍዦಒ झᙖҗ!PCDN!ᡣjoufhsjot߄౜ϝε೽ϩࢂ҂ޕޑǶӧ೭္ךॺᙖҗࢬԄಒझሺϩ݋

ว౜!PCDN!ቚу!ȕ2!ک!ȕ4!joufhsjot߄౜ǴӢԜӧဍዦᙯ౽ਔתᄽ๱ख़ाޑفՅǶ ӧҞ߻ޑࣴزǴךॺΨ٬Ҕȕ2!ک!ȕ4!joufhsjotޑൂਲ਼לᡏѐᢀჸ!ȕ2!ک!ȕ4!ޑف ՅǴ٠Ъว౜Ѭૈ׭ڋҗ!PCDN!ᇨᏤޑಒझᙯ౽Ǵ߄Ң!ȕ2!ک!ȕ4!ёૈୖᆶӧ!PCDN!

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ᇨᏤ߻ӈဏဍዦಒझᙯ౽Ϸjoufhsjot߄౜Ƕ׳຾΋؁Ҕ!ȕ2!ک!ȕ4!tjSOB!ٰว౜

ૈ୼׭ڋ!PCDN!ᇨᏤဍዦಒझᙯ౽ࢲ୏ૈΚǴࡰр!ȕ2!ک!ȕ4!ୖᆶӧ!PCDN!ፓ௓ဍ ዦಒझᙯ౽ύǶќѦǴஒಒझଌΕCNQ.3!tjSOB෧ϿҗPCDNᇨᏤቚу!ȕ2!ک!ȕ4!

joufhsjot߄౜ǶCNQ.3Ψёаቚу߻ӈဏဍዦಒझ΢!ȕ2!ک!ȕ4!joufhsjot߄౜Ƕ!

!!!!ϐ߻ൔ֋ࡰрǴӭᅿғߏӢηڈᐟ!joufhsjo!ࢲϯࢂ࿶җ!OG.țC!ᙯᒵԶٰ!

ȐIvboh!fu!bm/-!3118ȑǶΨԖൔᏤࡰр!Blu!ک!FSL203!ၡ৩ёᇨᏤ!OG.țC!ᙯᒵ Ӣη߄౜ȐLbujzbs!fu!bm/-!3118ȑǶ!ҔPCDNڈᐟ߻ӈဏᕎಒझёᇨᏤ!Blu!ک!FSL ࢲϯǶ!٣߻๏ϒ!FSL׭ڋᏊ!QE:916:!ک!QJ4L׭ڋᏊ!MZ3:5113!෧ϿҗPCDNቚу߻

ӈဏဍዦಒझ౽Չکjoufhsjot߄౜ǶҔ!nvubou!ޑ!Blu!ک!FSL!׭ڋҗ!PCDN!܌ቚ மಒझᙯ౽ޑૈΚǴёаӆԛዴۓ೭ঁ่݀Ƕന߈ΨԖൔ֋ࡰрࢲϯ!Blu!ک!FSL!ၡ ৩ૈᇨᏤjoufhsjot߄౜ȐMfwz!fu!bm/-!3114ȑǶNbutvp!fu!bm/Ȑ3117ȑࡌ᝼!Blu!

ک!FSL!ၡ৩ୖᆶܭ!gjcspofdujo!ѐᇨᏤ!Įv!joufhsjot߄౜ϐύǶќѦǴCNQ.3!

tjSOBߔᘐΑҗPCDNᇨᏤቚу!Blu!ک!FSL!ᕗለϯǶӢԜǴࢲϯ!Blu!ک!FSL!ჹܭ Ptufpcmbtut.efsjwfe!CNQ.3ӧΓᜪ߻ӈဏಒझ΢ᇨᏤޑ౽Չکjoufhsjot߄౜ёૈ

תᄽ๱ख़ाޑفՅǶ

!!!!೚ӭൔ֋ࡰрOG.țCޑࢲϯࢂୖᆶӧjoufhsjot߄౜کဍዦᙯ౽྽ύȐIvboh!fu!

bm/-!3118ȑǶӧҁჴᡍύǴךॺ᛾ჴPCDNᇨᏤޑ౽Չکjoufhsjot߄౜ё೏OG.țC

׭ڋᏊǴQEUDکUQDLٰ׭ڋǴӢԜࢲϯOG.țCёૈୖᆶӧPCDNᇨᏤjoufhsjot߄౜ϐ ύǶӧόࢲϯޑރᄊΠǴOG.țCᙖҗ׭ڋೈқINBޑ׭ڋǴԶ҅தӦߥ੮ӧಒझ፦྽

ύǶӧႽࢂUOG.ĮڈᐟࡕǴJțCೈқᙖҗJLL!ፄӝᡏஒځᕗለϯǴՔᒿԶٰޑࢂJțC

೏vcjrvjujobujpoǴ٠Ъᒿࡕ೏37Tೈқ䁙फ़ှǶനࡕ೏ញܫޑOG.țCᙯᒵډਡϣǴ Զࢲϯϸᔈޑ୷ӢȐWfsnfvmfo!fu!bm/-!3114ȑǶӧҁࣴزǴךॺว౜ኪ៛ӧPCDN ΠޑQD4ಒझ೷ԋቚуΑJLL-!JțCϷQ76ᕗለϯǶճҔusbotjfou!usbotgfdujpo!

țC.mvdjgfsbtfٰϸᔈOG.țCࢲ܄ǴךॺΨว౜PCDNёቚуOG.țCࢲ܄Ƕӧ೭ঁࣴز྽

ύǴךॺว౜PCDNᇨᏤJLL-!JțCĮʳ کq76ᕗለϯ೏!QE:916:!ک!Mz3:5113!׭ڋǶ CNQ.3!tjSOB!Ψ෧ϿΑҗPCDNቚуJLL-!JțCĮکq76ᕗለϯǶ೭٤่݀ࡰрBluکFSL ёૈתᄽ࿶җJLLĮ/ȕѐቚуq76ᕗለϯکቚமOG.țCᙯᒵࢲϯբҔǶ!

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20

่ፕ!

!!!!ҁࣴزךॺว౜Α΋ঁཥޑᐒڋӧ!Ptufpcmbtu.efsjwfe!CNQ.3ፓ௓߻ӈဏဍ ዦಒझ౽Չࢂᙖҗቚу!ȕ2!ک!ȕ4!joufhsjot߄౜ǶԶ!Ptufpcmbtu.efsjwfe!CNQ.3 ቚуಒझᙯ౽کjoufhsjot߄౜ࢂᙖҗࢲϯ!Blu-!FSL-!JLLĮ/ȕ ک!OG.țC!ၡ৩ȐGjh/!

22*Ƕ!

!

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!

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22

!

Gjh/!2.2!PCDN.efsjwfe!CNQ.3!joevdfe!uif!njhsbujpo!bdujwjuz!pg!ivnbo!qsptubuf!

dbodfs!dfmmt/!

)B*!QD4!boe!EV256!dfmmt!xfsf!jodvcbufe!xjui!wbsjpvt!dpodfousbujpot!pg!PCDN-!

boe!jo!wjusp!njhsbujpo!bdujwjujft!nfbtvsfe!xjui!uif!Usbotxfmm!bgufs!35!is!

tipxfe!bmm!tvqqpsufe!uif!dfmmt!njhsbujpot!jo!b!dpodfousbjpo.efqfoefou!xbz/!

)C*!MoDbQ!dfmmt!xfsf!jodvcbufe!xjui!wbsjpvt!dpodfousbujpot!pg!PCDN-!boe!jo!

wjusp!njhsbujpo!bdujwjujft!nfbtvsfe!xjui!uif!Usbotxfmm!bgufs!35!is/!)D*!

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difnpljof!sfdfqupsǴ຾Զߦ٬ဍዦಒझ΢ޑjoufhsjotࢲϯȐTqsjohfs-!2::5ȑǶ!Ӣ ࣁjoufhsjotჹܭಒझᗹߕډಒझѦ୷፦ϩηࢂ߃ભௗڙᏔǴдॺჹܭಒझૻ৲໺ሀ תᄽΑख़ाޑᚈӛ໺ᏤفՅǴፓ௓ಒझޑӸࢲǴϩϯǴቚғǴ౽Չکಔᙃख़ཥ༟೷

ȐHjbodpuuj!boe!Svptmbiuj-!2:::ȑǶဍዦಒझଶ੮ӧՈᆅ྽ύǴаϷӧՈࢬύ౽ ՉǴჹܭဍዦޑᙯ౽ࢂόё܈લޑӢનǴฅԶǴĮwȕ4!joufhsjot!תᄽ๱ᜢᗖفՅ ӧፓ௓ဍዦಒझଶᅉӧՈࢬ྽ύȐQjmdi!fu!bm/-!3113ȑȐGjh/!26ȑǶӧځдЎക

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྽ύΨൔ֋!Įwȕ4!joufhsjot!ჹဍዦ׎ԋӕኬԖ๱ख़ाޑᜢ߯ȐCspplt!fu!bm/-!

2::5ǹCspplt!fu!bm/-!2::6ȑǴԜѦǴĮwȕ4!ک໵Յનዦ຾৖ԖᜢǴёڐշဍዦಒ झᗹߕډFDNǴ໔ௗӦ೷ԋဍዦᙯ౽ډޤ᠌ȐHpoh!fu!bm/-!3118ȑǶ

!!!!ޤ᠌़ғޑғߏӢηک!difnpljoft!Ψתᄽ๱ᔼᎦޑਡЈفՅѐ֎Їᓐᓍ೽

ᕎǵ٢ᕎǵ१ၰᕎᙯ౽ډޤ᠌ಔᙃǶԶځύς೏פډޑUHG.ȕࢂ೷ԋ٢ᕎᙯ౽ډޤ

᠌ޑЬाӢηȐXfmn!fu!bm-!3119ȑǶTEG.2Į ୷ҁҗΓᜪମᡎϣ!tuspnbm!dfmmϩ ݜǴЬाբҔӧମᡎ྽ύޑՈౚྍಒझ!ifnbupqpjfujd!dfmmtȐIQDȑǴߦ٬!IQD!ள аߥ੮ӧମᡎ໔ሜύғߏϷϩϯǴᗋԖᔅշCరЃౚԋዕวػȐCvshfs!boe!Ljqqt-!

3117ȑǶฅԶǴTEG.2Į ӧjoufhsjot΢ޑ߄౜ک౽ՉૈΚޑቹៜΚϷΓᜪ೬ମԺዦ ಒझᙯ౽ϝࢂ҂ޕޑǶ೭္ךॺว౜!TEG.2Į ቚу೬ମԺዦಒझ΢!joufhsjot!߄

౜Ϸ౽ՉǶԜѦǴDYDS5-!FSL-!JLLĮ/ȕ!boe!OG.țC!tjhobmjoh!qbuixbzt!ёૈୖᆶ ӧ!TEG.2Į ቚуjoufhsjot߄౜کಒझ౽Չ྽ύǶ!

!

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35

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djsdvmbujpo!boe!qspevdf!beejujpobm!nfubtubtft/!ȐBebqufe!gspn!Gjemfs-!3114ȑ

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)c*!Difnpljoft!efsjwfe!gspn!dbodfs!dfmmt!jo!dbodfs!qsphsfttjpo/!ȐBebqufe!

gspn!Lfjjdij!fu!bm/-!3118ȑ!

!

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37

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eftusvdujpo/ȐBebqufe!gspn!Cvshfs!boe!Ljqqt-!3117ȑ!

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Cfmmbidéof!fu!bm/-!3119ȑ!

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!

่݀ᆶ૸ፕ!

ȐSftvmut!boe!Ejtdvttjpoȑ!

!

(50)

่݀!

TEG.2Į0DYDS5 ҬϕբҔቹៜ೬ମԺዦಒझޑᙯ౽!

!!!!ҁჴᡍךॺࣴزࢂց TEG.2Įʳ ᆶ೬ମԺዦಒझᙯ౽ԖᜢǶTEG.2Į ჹܭ೬ମԺዦ ಒझޑᙯ౽ᙖҗ TEG.2 ܌ЇଆޑಒझቚғԭϩКٰਠ҅ȐDiv!fu!bm/-!3118ȑǶ๏

ϒόӕᐚࡋ TEG.2Į ёаቚу೬ମԺዦಒझޑᙯ౽ȐGjh/27BȑǶޤ΢Ҝಒझޑ dpoejujpo!nfejvn!ȐDNȑΨޔௗቹៜ೬ମԺዦಒझޑᙯ౽ȐGjh/27CȑǶTEG.2Į!tjSOB ёа׭ڋҗ DN ܌ቚу೬ମԺዦಒझޑᙯ౽ȐGjh/27DȑǶ!TEG.2Į ک DN Ψቹៜቚу ќѦ΋ਲ਼೬ମԺዦಒझ TX2464ȐGjh/27EȑǶҗܭϐ߻ൔᏤၸǴ!TEG.2Į کѬಒझ ߄य़΢੝ۓޑௗڙᏔ DYDS5 Ԗ஑΋ޑೱ่Ǵ٠Ъ཮ᇨᏤဍዦಒझᙯ౽ȐCvshfs!boe!

Ljqqt-!3117ǹLbcbtijnb!fu!bm/-!3118ȑǶӢԜǴךॺགྷவᖏ׉ੰΓي΢ӆԛѐӑ

᛾ǴࢂցੰΓಔᙃύ੿ޑԖၨӭޑ DYDS5 ߄౜Ƕவ SU.QDS ޑ่݀྽ύǴёаҗ೬ମ ԺዦੰΓي΢ڗளޑಔᙃᔠᡏύว౜ޑዴԖεໆ DYDS5 ߄౜ȐGjh/28BȑǶӢԜǴך ॺᢀჸࢂց TEG.2Į0!DYDS5 ҬϕբҔࢂୖᆶӧ೬ମԺዦಒझᙯ౽ύǶவࢬԄಒझሺ ޑ่݀ࡰр TEG.2Į ܴᡉӦቚуΑಒझ߄य़΢ DYDS5 ߄౜ȐGjh/28CȑǶऩ٣Ӄ๏ϒ ಒझ DYDS5!joijcjupsȐBNE4211ȑǵ!DYDS5!Bc!)21oh0nm*!ೀ౛ 41 ϩដǴ܈ᙯ෗

DYDS5!tjSOB!35 λਔࡕǴว౜೿ૈ୼׭ڋҗ TEG.2Į ᇨᏤဍዦಒझᙯ౽ȐGjh/28DȑǶ ೭٤่݀ࡌ᝼ TEG.2Į0DYDS5 ҬϕբҔୖᆶΑ೬ମԺዦޑᙯ౽ϐύǶ!

!

TEG.2Į ቚу೬ମԺዦಒझ΢ Įwȕ4!joufhsjot ߄౜!

!!!!Ӄ߻ԖࣴزᡉҢӧΓᜪᕎಒझύ!Įw!ک!ȕ4!!joufhsjot Ԗܴᡉޑ߄౜ȐTvo!fu!

bm/-!3118ǹ[ibp!fu!bm/-!3118ȑǶךॺௗ๱ଷ೛ joufhsjot ёૈୖϒӧ TEG.2Į ᇨᏤ೬ମԺዦಒझޑᙯ౽྽ύǶࢬԄಒझሺϩ݋ᡉҢǴ٩ਔ໔ᗺ๏ϒ TEG.2Į ቚу ဍዦಒझጢ΢ Įvȕ3 joufhsjot ߄౜ǴԶ Į5ȕ1 ܈ Į2ȕ1 joufhsjot ߾ؒԖቹៜ ȐGjh/29BȑǶஒಒझ๏ϒ!Įvȕ3 Bc!ǵ!SHE!qfqujefǴૈ୼׭ڋҗ TEG.2Į ܌ᇨᏤ ޑဍዦಒझᙯ౽ǴԶ SBE!qfqujef ߾ؒԖቹៜȐGjh/29CȑǶӢԜǴTEG.2Į ࢂ࿶җ ፓ௓ቚу Įvȕ3 joufhsjot ٰቚу೬ମԺዦಒझޑᙯ౽Ƕ!

!

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40

FSL203!tjhobmjoh!qbuixbz!ୖᆶӧҗ TEG.2Į ፓ௓ቚу joufhsjot аϷ೬ମԺዦಒ झޑᙯ౽ύ!

!!!!ӧ೚ӭဍዦಒझ΢ǴTEG.2Į0DYDS5 ޑҬϕբҔᡉҢჹܭಒझᙯ౽Ԗख़ाޑ౐

ೱǶԶځύ!NBQLȐnjuphfo.bdujwbufe!qspufjo!ljobtftȑᇡࣁѬࢂဍዦಒझ຾৖

ރᄊΠޑख़ाၡ৩ȐTfcpmu.Mpqpme!boe!Ifssfsb-!3115ȑǶךॺௗΠٰճҔՋБᗺ Ꮐݤѐࣴز TEG.2Į ᇨᏤဍዦಒझᙯ౽ޑૻ৲໺ሀၡ৩Ƕ๏ϒ TEG.2Į ܭ KK ಒझቚ уΑಒझϣ FSL203!ޑᕗለϯǴԶ Q49 ܈ KOL ٠คቹៜȐGjh/2:BȑǴ!q49 Ϸ KOL!nvubou ٠คԜբҔǶஒಒझ๏ϒ FSL ޑ׭ڋᏊ QE:916:!)21ȝN*ૈ׭ڋҗ TEG.2Į ᇨᏤޑဍ ዦಒझᙯ౽ǴԶ Q49 ޑ׭ڋᏊ TC314691 ᆶ KOL ޑ׭ڋᏊ TQ711236 ٠คቹៜ ȐGjh/2:CȑǶஒ FSL3!nvubou ଌΕಒझǴΨૈ׭ڋҗ TEG.2Į ᇨᏤ KK ಒझᙯ౽ ȐGjh/2:DȑǶԜѦǴĮvȕ3ǴFSL ׭ڋᏊک FSL3!nvubou ࣣૈ୼׭ڋҗ TEG.2Į ܌ᇨ Ꮴ KK ಒझ΢ Įwȕ4!joufhsjot ޑ߄౜ȐGjh/2:EȑǶӢԜǴFSL203!ૻ৲໺ሀࢂୖᆶ ӧҗ TEG.2Į ፓ௓ቚу joufhsjot ߄౜ک೬ମԺዦಒझޑᙯ౽Ƕ!

!

OG.țC!tjhobm!qbuixbz ୖᆶӧҗ TEG.2Į ፓ௓ቚу joufhsjot аϷ೬ମԺዦಒझޑ ᙯ౽!

!!!!ϐ߻ൔ֋ࡰр OG.țC ک BQ.2 ᙯᒵӢηୖᆶӧ TEG.2Į ᇨᏤޑಒझᙯ౽྽ύǶஒ ಒझଌΕ OG.țC!PEOȐpmjhpefpyzsjcpovdmfpujefȑǴёа෧Ͽҗ TEG.2Į ܌ᇨᏤޑ ಒझᙯ౽ǴԶ BQ.2!PEO ٠คԜբҔȐGjh/31BȑǶӢԜǴOG.țC ࢂၨख़ाܭ TEG.2Į ᇨᏤޑಒझᙯ౽྽ύǶӕኬޑ٬ҔΑ JțCĮ!qspufbtf!׭ڋᏊ UQDLȐ4ȝNȑǵOG.țC!׭

ڋᏊ QEUDȐ21ȝNȑǴϷ OG.țC!joijcjups!qfqujef!Ψ೿׭ڋΑҗ TEG.2Į ᇨᏤ KK ಒझޑᙯ౽ȐGjh/31CȑǶӢԜǴOG.țC!ᙯᒵӢηୖᆶӧҗ TEG.2Į ᇨᏤ೬ମԺዦಒ झޑᙯ౽྽ύǶௗΠٰךॺࣴز TEG.2Į ᇨᏤ OG.țC!ౢғࢲ܄ޑ΢ෞӢηǶ!ಒझ๏

ϒ TEG.2Į!ቚуΑಒझ፦ύ JLLĮ0ȕ ǵ!JțCĮ ޑᕗለϯǴаϷਡϣᆫ໣Αᕗለϯޑ q76ȐGjh/32BȑǶӢԜǴJLL ک OG.țC!!tjhobm!qbuixbz ࢂୖᆶӧ TEG.2Į ᇨᏤ೬ମ Ժዦಒझᙯ౽྽ύǶനࡕǴךॺҔ țC!qspnpufs!bttbz!ѐዴᇡ OG.țC ࢲ܄Ƕ๏ϒಒ झ!BNE4211!ǵ!QE:916:!ǵ!QEUD!ǵ!UQDL!܈ࢂ!dpusbotgfdujpo!DYDS5tjSOB!ǵ!

FSL!ǵ!JLLĮ ǵ!JLLȕ!nvubou ډಒझϣǴ೿ૈ෧Ͽҗ!TEG.2Į ᇨᏤቚу!OG.țC!

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qspnpufs ࢲ܄ȐGjh/32CȑӢԜǴDYDS50FSL!ک!OG.țC!tjhobm!qbuixbz ࢂୖᆶӧ!

TEG.2Į!ᇨᏤޑಒझᙯ౽྽ύǶ!

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૸ፕ!

!!!!ဍዦಒझᙖҗಔᙃલ਼ǵѨѐፓ࿯ᙯᒵޑ௓ڋӢη܈ࢂࢲϯႀ਽ለᐟ䁙ௗڙᏔ

ޑБԄǴᇨᏤԾيಒझ΢DYDS5߄౜Ǵٗሶҗܭ኱ޑᏔ۔ϩݜрᙦ൤ޑ!TEG.2ĮǴΨ ൩཮ᇨᏤဍዦಒझ߻۳኱ޑᏔ۔౽୏ǴӢԶගٮΑ΋ঁᙯ౽ޑᐒڋȐTubmmfs!fu!bm/-!

3114ȑǶ೬ମԺዦಒझڀԖޑ໼ӛǴ൩ࢂ৒ܰᙯ౽ډޤ᠌ȐKbnciflbs!fu!bm/-!2::8ȑǶ ѐϩ݋௓ڋ೬ମԺዦဍዦಒझᙯ౽ډޤ᠌ޑૻဦǴࢂख़ाܭჹלᕎੱᙯ౽ݯᕍǶך ॺଷۓ!TEG.2Į ૈޔௗߦ຾೬ମԺዦಒझᙯ౽Ƕךॺว౜җޤ᠌ϩݜрޑ!TEG.2Į ᇨᏤΑ೬ମԺዦಒझޑᙯ౽Ƕ!TEG.2Į ೷ԋᙯ౽ޑځύᐒڋǴࢂᙯᒵፓ௓ቚу!Įvȕ3!

joufhsjot!߄౜Ϸࢲϯ!DYDS5-!FSL-!JLLĮ/ȕ!ک!OG.țC!ၡ৩Ƕ!

!!!Ӄ߻ޑࣴزᡉҢӧኧᅿᕎੱ΢ǴĮvȕ3!joufhsjotࣣፓ௓Αဍዦಒझޑᙯ౽Ϸߟ ΕȐCspplt!fu!bm/-!2::5ǹCspplt!fu!bm/-!2::6ǹQjmdi!fu!bm/-!3113ǹ!Hpoh!fu!

bm/-!3118ȑǶฅԶǴӧΓᜪޑ೬ମԺዦಒझᙖҗ!TEG.2Į ѐቚу!joufhsjot!߄౜

ϝε೽ϩࢂ҂ޕޑǶӧ೭္ךॺᙖҗࢬԄಒझሺϩ݋ว౜!TEG.2Į ቚу!Įv!ک!ȕ3!!

joufhsjot!߄౜ǶӧҁࣴزύǴךॺ٬Ҕ Įv!ک!ȕ3!joufhsjotޑൂਲ਼לᡏѐᢀჸ!

Įv ک!ȕ3!ޑفՅǴว౜Ѭૈ׭ڋҗ!TEG.2Į ᇨᏤޑಒझᙯ౽Ǵ߄Ң!Įv!ک!ȕ3!ჹ ܭ!TEG.2Į ᇨᏤ೬ମԺዦಒझᙯ౽Ϸ!joufhsjot!߄౜΢ԖᜢǶ׳຾΋؁Ҕ!SHE!

qfqujef!ٰዴۓૈ୼׭ڋ!TEG.2Į ᇨᏤቚமᙯ౽ࢲ୏ૈΚǴࡰр!Įvȕ3 joufhsjot!

ࢂୖᆶӧ!TEG.2Į ቚуဍዦಒझᙯ౽ϐύǶ!

!!!!ࢌ٤!difnpljoft!ς೏᛾ჴёаගٮಔᙃ੝౦܄ޑᇨᏤӢηܭဍዦಒझǴ٠ߦ

຾ဍዦಒझ౽Չډ੝ۓޑ೽ՏȐPeb!fu!bm/-!3117ȑǶӧdifnpljoftکѬॺޑ!

sfdfqups!྽ύǴ!TEG.2Į0DYDS5!س಍ς೏᛾ჴࢂୖᆶӧరЃ่ᙯ౽܈ӭᅿᕎੱޑ ᇻᆄᙯ౽྽ύȐNýmmfs!fu!bm/-!3112ǹTdpuupo!fu!bm/-!3112ǹSvttfmm!fu!bm/-!

3115ȑǶDYDS5!߄౜کᙯ౽ၸำԖ๱ख़ाޑ౐ೱǴTEG.2Į0DYDS5!ၡ৩ς೏᛾ჴࢂ

ୖᆶӧମԺዦȐptufptbsdpnbȑᙯ౽ډޤ᠌ၸำ྽ύȐQfsjttjopuup!fu!bm/-!3116ȑǶ ךॺว౜!TEG.2Į ӧ೬ମԺዦಒझቚமΑ!FSL203!ᕗለϯǶ!TEG.2Įޔௗቹៜ೬ମ Ժዦಒझᙯ౽ک!joufhsjot!߄౜೏!BNE4211!ǵ!DYDS5!Bc!ک!QE:916:!׭ڋǶճҔ!

DYDS5!tjSOB!ک!FSL!nvubou!ё׭ڋҗ!TEG.2Į ܌ቚமಒझᙯ౽ޑૈΚǶךॺޑ่

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݀ࡰр!DYDS5!ک!FSL!ёૈჹܭ!Įvȕ3 joufhsjot!߄౜کΓᜪ೬ମԺዦಒझᙯ౽΢

תᄽख़ाޑفՅǶ!

!!!!OG.țC ΋ ૓ ޑ ࢲ ϯ ၡ ৩ ࢂ ࿶ җ JțCĮ ᕗ ለ ϯ Ǵ ௗ ๱ ᒿ ϐ Զ ٰ ஒ ځ ᆫ ݱ ન ȐqpmzvcjrvjujobujpoȑǴനࡕ཮೏37Tೈқ䁙Ȑqspufbtpnfȑफ़ှ௞ǴOG.țC!ejnfst ӢԜ೏ញܫ٠ᙯᒵډਡϣǴӧԜѬॺ่ӝډOG.țCϸᔈ୷ӢޑଆۈՏ΢Ǵѐፓ௓୷Ӣ ޑ߄౜ǴӢԜǴOG.țCᙯᒵࢲϯޑૈΚૈ୼೏ᕗለϯ܌ፓ௓ȐCfjolf!!boe!Mfz-!

3115ȑǶڂࠠޑOG.țCࢲϯၡ৩ࢂҗ߻วݹಒझᐟનǵלচǵಒ๵ಒझᏛԋϩނǵੰ

ࢥǵ୷Ӣࢥ܄ᓸΚ฻ٰЇวǴӧၡ৩྽ύq610q76౦ᚈᡏȐifufspejnfsȑޑᙯᒵբ ҔȐusbotmpdbujpoȑࢂᙖҗӃЇว٩ᒘJțCޑݱનϯȐvcjrvjujobujpoȑϷफ़ှǴ

ٰߦ٬q76౦ՏډਡϣȐJopvf!fu!bm/-!3118ȑǶԖൔᏤࡰр!UOG.Į!࿶җᇨᏤ!JLLt!

זೲӧ!q76!Tfs^647!ᕗለϯǴ೷ԋቚу!q76!ޑᙯᒵࢲ܄ȐTblvsbj!fu!bm/-!2:::ȑǶ ךॺჴᡍ่݀ᡉҢ!DYDS5!ک!FSL!ёૈ࿶җ!JLLĮ/ȕ^!ѐቚу!q76!ӧ!Tfs^647!ᕗለϯ ٠ቚம!OG.țC!ᙯᒵૈΚǶ!

่ፕ!

!!!!ךॺӧ೭္ว౜΋ঁཥޑᐒڋӧ೬ମԺዦಒझޑᙯ౽΢Ƕҗޤ᠌ϩݜԶٰޑ!

TEG.2Įʳ ቚу೬ମԺዦಒझᙯ౽ک!Įvȕ3!joufhsjot!߄౜ࢂᙖҗࢲϯ!DYDS5-!FSL-!

JLLĮ/ȕ!ک!OG.țC!ၡ৩ȐGjh/!33*Ƕ

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Gjh/!3.2!!TEG.2Į joevdfe!uif!njhsbujpo!pg!dipoesptbsdpnb!dfmmt/!

Dipoesptbsdpnb!dfmmt!xfsf!jodvcbufe!xjui!wbsjpvt!dpodfousbujpot!pg!TEG.2Į )B*-!KK!dfmmt!xfsf!jodvcbufe!xjui!wbsjpvt!dpodfousbujpot pg!mvoh!fqjuifmjvn!

dfmmt! dpoejujpofe! nfejvn! )DN*/ Ȑ C ȑ ! boe!jo! wjusp! njhsbujpo! bdujwjujft!

nfbtvsfe!xjui!uif!Usbotxfmm!dibncfs!bgufs!35!is!tipxfe!uif!jodsfbtf!pg!uif!

njhsbujpo!pg!dipoesptbsdpnb!dfmmt!jo!b!eptf.efqfoefou!nboofs/ȐDȑ Mvoh!

fqjuifmjvn!dfmmt!xfsf!usbotgfdufe!xjui!TEG.2Į ps!dpouspm!tjSOB!gps!35!is-!

uif!nfejvn!xbt!dpmmfdufe!bt!dpoejujpofe!nfejvn-!boe!jo!wjusp!njhsbujpo!xbt!

nfbtvsfe! xjui! uif! Usbotxfmm! dibncfs! bgufs! 35! is/! TEG.2! tjSOB! nbslfemz tvqqsfttfe!uif!DN.joevdfe!njhsbujpo!jo!KK!dfmmt/ȐEȑDipoesptbsdpnb!dfmm!

mjofȐTX2464ȑ!xfsf!jodvcbufe!xjui!TEG.2Į ps!DNȐ86&ȑgps!35is/!Cpui!pg!TEG.2Į boe!DN!joevdfe!dfmm!njhsbujpo/!Sftvmut!bsf!fyqsfttfe!bt!uif!nfbo!²!T/F/!+-!

q!=!1/16!dpnqbsfe!xjui!dpouspm/!$-!q!=!1/16!dpnqbsfe!xjui!DN.usfbufe!hspvq/!

)o>5*/!

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!

Gjh/!3.3!!TEG.2Į0DYDS5!ejsfdufe!difnpnjhsbujpo!pg!ivnbo!dipoesptbsdpnb!

dfmmt/!

Ȑ B ȑ Upubm! SOB! xfsf! fyusbdufe! gspn! opsnbm! dbsujmbhf! )mjof! Q2.Q3*! boe!

dipoesptbsdpnb!qbujfout!)mjof!Q4.Q6*-!boe!tvckfdufe!up!SU.QDS!bobmztjt!gps!

DYDS5/ȐCȑKK123!dfmmt!xfsf!jodvcbufe!xjui!TEG.2Į )211!oh0nm*!gps!joejdbufe!

ujnf!joufswbmt-!boe!uif!dfmm!tvsgbdf!fyqsfttjpo!pg!DYDS5!xbt!efufsnjofe!vtjoh!

gmpx!dzupnfusz/ȐDȑQsfusfbunfou!pg!dfmmt!xjui!TEG.2Į!joijcjups!BNE4211-!

DYDS5!boujcpejft!ps!usbotgfdujpo!xjui!DYDS5!tjSOB!joijcjufe!TEG.2Į.joevdfe!

KK!dfmmt!njhsbujpo/!Sftvmut!bsf!fyqsfttfe!bt!uif!nfbo!²!T/F/!+-!q!=!1/16!

dpnqbsfe!xjui!dpouspm<!$-!q!=!1/16!dpnqbsfe!xjui!TEG.2Į.usfbufe!hspvq/!)o>5*/

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!

Gjh/!3.4!!Sfhvmbujpo!pg!Įvȕ3!joufhsjot!jt!jowpmwfe!jo!TEG.2Į0DYDS5.!

ejsfdufe!difnpnjhsbujpo!pg!ivnbo!dipoesptbsdpnb!dfmmt!jowpmwft!vq./!

ȐBȑKK!dfmmt!xfsf!jodvcbufe!xjui!TEG.2Į )211!oh0nm*!gps!joejdbufe!ujnf!

joufswbmt-!boe!uif!dfmm!tvsgbdf!fyqsfttjpo!pg!Įwȕ4-!Į6ȕ2!ps!Į3ȕ2!joufhsjo xbt!efufsnjofe!vtjoh!gmpx!dzupnfusz.ȐCȑKK!dfmmt!xfsf!qsfusfbufe!xjui!Įwȕ4 npopdmpobm!boujcpez!)21!Ph0nm*-!dzdmjd!SHE!)211!oN*!ps dzdmjd!SBE!)211!oN*!

gps!41!njo!gpmmpxfe!cz!tujnvmbujpo!xjui!TEG.2Į )211!oh0nm*/!Uif!jo!wjusp njhsbujpo!bdujwjuz!nfbtvsfe!bgufs!35!is!tipxfe!uibu!Įwȕ4 npopdmpobm!boujcpez!

boe!dzdmjd!SHE!cvu!opu!dzdmjd!SBE!joijcjufe!uif!TEG.2Į joevdfe!njhsbujpo!

bdujwjujft/!Sftvmut!bsf!fyqsfttfe!bt!uif!nfbo!²!T/F/!+-!q!=!1/16!dpnqbsfe xjui!dpouspm<!$-!q!=!1/16!dpnqbsfe!xjui!TEG.2Į.usfbufe!hspvq/!)o>5*/!

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