一、 由於原發型自發性氣胸（PSP）至今並無單一的國際疾病分類碼
（ICD-9）可對應，造成研究個案數的受限，，個案的來源需由個別 醫院病歷中逐一挑選無法使用健保資料庫進行大量而全面性的篩 選。至今相關文獻也缺乏大型的隨機控制研究（Randomised controlled trials；RCT）。
二、 本研究採保險人觀點來分析，以健保費用支付標準作為費用計 算，雖可清楚地瞭解保險支付端的成本，卻無法直接反映醫療耗用之 實際成本。
三、 有關氣胸治療後再復發之確認，部份個案採電話追蹤，可能會有 記憶偏差存在與研究個案失聯之情況。第一項限制因素，也影響到利 用健保資料庫追縱個案於國內再就醫之情況。
四、 視訊輔助胸腔鏡手術（VATS）之施行需由專科醫師執行,醫師之 訓練及技術對復發率的影響及健保施行期間支付標準的改變，由於兩 組個案皆來訪自相同的時空區間，因此在分組收案時已盡量排除相關 影響。
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