[PDF] Top 20 Association of IL12B polymorphisms with susceptibility to Graves ophthalmopathy in a Taiwan Chinese population

... located in the promoter region of the IL12B gene, may be associated with GO ...tried to analyze its genotype distribution in our patients, but we failed to ... See full document

... consistent with our results from LD ...prediction of development of GD and GO by different IL1B ...that a positive feedback cycle composed of mechanical, immunologic, and ... See full document

... inability to understand or give informed consent and pregnant or given birth within 1 year to exclude patients with postpartum ...thyroiditis. Graves' ophthalmopathy was identified ... See full document

... Lutterotti A, Ingram J, Schanda K, Gassner C, Deisenhammer F, Berger T, Lorenz E: Mutations in the gene for toll-like receptor 4 and multiple ...G299D polymorphisms are not associated with ... See full document

... Collection A total of 471 patients with GD visiting at China Medical Uni- versity Hospital, Taiwan, were enrolled in this ...endocrinologist with substantial experience in ... See full document

... Department of Physical Medicine and Rehabilitation, 2 Department of Medical Genetics; 4 Division of Immunology and Rheumatology, Department of Internal Medicine; 5 Department of ... See full document

... minor A allele frequencies of Cav-1 G14713A are 22.1% in our control group, close to those of ...populations in NCBI, which strongly suggest no selection bias for the ... See full document

... these polymorphisms to these chronic inflammatory diseases still remain unknown, the extremely complex signaling network could be regulated at essentially every step, especially considering that the EGFR ... See full document

... marker of different genetic factors in RA development. Moreover, due to the limited subject number from one medical center in our study, larger scale studies for further confirmation of ... See full document

... Study population and sample ...diagnosed with prostate cancer were recruited at the outpatient clinics of general surgery between 2003-2009 at the China Medical University Hospital, Taichung, ... See full document

... composed of 129 patients with biopsy-diagnosed IMN and a gender-matched control group composed of 106 healthy individuals, identified through health examination at Taichung Veterans General ... See full document

... evaluated in the Taiwanese population. We investigated the association of IL-10 and TNF-α promoter polymorphisms (-1082, -819 and -592 for IL-10 gene; -308 for TNF-α gene) ... See full document

... effects of these intronic SNPs on the G protein, they were associated with SOC therapy ...associated with therapeutic outcomes, the linkage among these GNB1 polymorphisms and RVR/SVR should be ... See full document

... Study Population A gender-age-matched control group composed of 265 non-diabetic, non-nephropathic, normotensive healthy unrelated control subjects, whom identified through health examination at ... See full document

... disease susceptibility of AD. Previous studies have shown that the IL-4–590T, IL-13 +4464A, IL-4R*R576, STAT6*13R, IL-12B +4237A, and TNF-a ... See full document

... genome-wide association studies are needed for further testing in different ...populations. Association study is the most important tool for identifying genes conferring susceptibility ... See full document

... Results A total of 210 subjects of Taiwanese Han Chinese comprised this study ...variants in the SETX gene were selected for this study: 3455T>G (rs3739922), 3576T>G (rs1185193) and ... See full document

... carrying a homozygous TT genotype at uPA rs4065 or at least 1 T allele at uPAR rs344781 had a tendency to develop advanced ...genotypes with NSCLC susceptibility in the present ... See full document

... trends of significant data after age- and behavior-adjustments strengthen the accuracy and reliability of our findings, and the fre- quencies of Cav-1 polymorphisms variant alleles were ... See full document

... differences in the allele or genotype distributions among patients with different grades of goiter in GD and healthy controls, the distribution of the C allele, especially C/C genotype, ... See full document