[PDF] Top 20 A beveled tip sheath liquid interface for capillary electrophoresis-electrospray ionization-mass spectrometry

... the interface in the cou- pling of MEKC with ESI-MS using SDS as the surfactant, a 20 ppm triazine mixture was hydrodynamically injected into the capillary using a 10 mbar pressure ... See full document

... surfactant, a 5 ppm triazine mixture was hydrodynamically injected into the capillary using a 10 mbar pressure differential for a duration of 10 ...makeup liquid was critical to ... See full document

... using a low-flow interface. A tapered CEC column was used in this ...with a column prepared using a sintered frit, the tapered column used in this study eliminated the problem of bubble ... See full document

... R.O.C A four-channel multiplexed electrospray capillary elec- trophoresis interface has been ...new interface permits up to four capillary electrophoresis columns to be ... See full document

... used for the above experiments all contain organic solvents, but most capillary electrophoresis analyses are performed in aqueous ...the mass spectrometer to perform the following experiments. ... See full document

... CE-MS interface Because of smaller initial droplets, it has been shown that low-flow ESI emitters, such as microspray and nano- spray, lead to better sensitivity over ESI conducted at higher flow rates ...of ... See full document

... makeup liquid in the interface may degrade the overall sensitivity, because the analyte band is diluted in a relatively large volume prior to being dispersed into a fine aerosol ...CE/ESI-MS ... See full document

... pK a and thus can be used over a wide pH ...is a popular buffer for CE-UV applications, transferring methods developed for CE with UV detection to CE with electrospray ... See full document

... be a better choice for the identification of chemical drugs in Chinese ...medicines. For example,four compounds were detected in one Chinese medicinal preparation,but,of these four compounds,three ... See full document

... the sheath liquid design is that the concentration of the analyte is substantially diluted due to the relatively high flow rate of sheath ...of a conductive layer such as gold on the ... See full document

... and mass spectrometry Mass spectrometry was performed using a Finnigan LCQ quadrupole ion trap mass spectrometer (Finnigan ...different electrospray sources were used: (1) ... See full document

... the sheath liquid used in normal CE (metha- tropherogram and the third and fourth peaks were nol–water, 80:20) containing ...adopted for reversed EOF CE–ESI-MS ...the mass spectrometer as the ... See full document

... imparts a considerable dilution of the sample bands, since the flow rate of CE is in the range of several hundred ...such a high flow rate in a conventional sheath liquid ... See full document

... probes for target species such as proteins [19,20], pep- tides [19,20], phosphopeptides [21,22], and pathogenic bacteria [23,24] followed by characterization of matrix-assisted laser desorption/ionization ... See full document

... investigated for use with capillary electrochromatography–mass spectrometry (CEC-MS) ...have a net velocity directed towards the buffer reservoir (inlet) over a wide range in pH, ... See full document

... The mass spectrometer was operated in positive ion mode by applying a voltage of ...heated capillary in the ESI source was set at 295 ...ions for full scan mode, 4 × 10 7 for MS/MS ... See full document

... it is possible to obtain useful mass electropherogram with 50 ppb level of most phenols, further improve- ment in sensitivity is needed for the detection of low[r] ... See full document

... [9] demonstrated the separation of gangliosides with different glycan structures but were unable to resolve gangliosides having the same glycans but different ceram[r] ... See full document

... amounts. Mass spectrometric techniques, especially the com- bination of soft ionization methods such as fast atom bombardment (FAB) with collision-induced dissociation (CID), have been used for ... See full document

... indicates a desirable ...demonstrated a quite straightforward approach involving the use of a tip operated by an electronic pipette as a spray emitter without any extra accessories or ... See full document